Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

SG Thavarajasingam, M El-Khatib, K Vemulapalli… - Acta …, 2023 - Springer
Background Patients with the dementia subtype idiopathic normal pressure hydrocephalus
(iNPH) may improve clinically following cerebrospinal fluid (CSF) diversion (shunt) surgery …

Plasma neurodegeneration biomarker concentrations associate with glymphatic and meningeal lymphatic measures in neurological disorders

PK Eide, A Lashkarivand, A Pripp, LM Valnes… - Nature …, 2023 - nature.com
Clearance of neurotoxic brain proteins via cerebrospinal fluid (CSF) to blood has recently
emerged to be crucial, and plasma biomarkers of neurodegeneration were newly introduced …

The pathogenesis of idiopathic normal pressure hydrocephalus based on the understanding of AQP1 and AQP4

Z Zhao, J He, Y Chen, Y Wang, C Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disorder without a
recognized cause. Aquaporins (AQPs) are transmembrane channels that carry water …

Novel cerebrospinal fluid biomarkers correlating with shunt responsiveness in patients with idiopathic normal pressure hydrocephalus

S Weiner, A Junkkari, M Sauer, A Luikku… - Fluids and Barriers of …, 2023 - Springer
Abstract Background Idiopathic Normal pressure hydrocephalus (iNPH) is a form of adult
hydrocephalus that is clinically characterized by progressive gait impairment, cognitive …

Unbiased CSF proteomics in patients with idiopathic normal pressure hydrocephalus to identify molecular signatures and candidate biomarkers

MB de Geus, CY Wu, H Dodge, SN Leslie, W Wang… - Neurology, 2025 - neurology.org
Background and Objectives Idiopathic normal pressure hydrocephalus (iNPH) is a
reversible neurologic disorder that remains poorly understood. Accurate differential …

A year in review: brain barriers and brain fluids research in 2022

RF Keep, HC Jones, MG Hamilton… - Fluids and Barriers of the …, 2023 - Springer
This aim of this editorial is to highlight progress made in brain barrier and brain fluid
research in 2022. It covers studies on the blood-brain, blood-retina and blood-CSF barriers …

[HTML][HTML] Cerebrospinal fluid biomarkers in iNPH: a narrative review

ES Pyrgelis, F Boufidou, VC Constantinides… - Diagnostics, 2022 - mdpi.com
Idiopathic normal pressure hydrocephalus (iNPH) is a neurological syndrome characterized
by the clinical triad of gait disorder, cognitive impairment and urinary incontinence. It has …

Cellular changes at the glia-neuro-vascular interface in definite idiopathic normal pressure hydrocephalus

PK Eide - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Idiopathic normal pressure hydrocephalus (iNPH) is a subtype of dementia with overlap
toward Alzheimer's disease. Both diseases show deposition of the toxic metabolites amyloid …

[HTML][HTML] Alzheimer's Disease CSF Biomarkers as Possible Indicators of Tap-Test Response in Idiopathic Normal Pressure Hydrocephalus

ES Pyrgelis, GP Paraskevas, VC Constantinides… - Brain Sciences, 2023 - mdpi.com
The aim of the present study is the evaluation of established Alzheimer's disease (AD)
cerebrospinal fluid (CSF) biomarkers in patients with idiopathic normal-pressure …

In vivo assessment of Lewy body and beta-amyloid copathologies in idiopathic normal pressure hydrocephalus: prevalence and associations with clinical features and …

G Giannini, S Baiardi, S Dellavalle, C Zenesini… - Fluids and Barriers of …, 2022 - Springer
Background Idiopathic normal pressure hydrocephalus (iNPH) is a clinico-radiological
syndrome of elderly individuals likely sustained by different neurodegenerative changes as …