Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview

F Brosseron, M Krauthausen, M Kummer… - Molecular …, 2014 - Springer
This article gives a comprehensive overview of cytokine and other inflammation associated
protein levels in plasma, serum and cerebrospinal fluid (CSF) of patients with Alzheimer's …

Role of inflammatory molecules in the Alzheimer's disease progression and diagnosis

E Bagyinszky, V Van Giau, K Shim, K Suk… - Journal of the …, 2017 - Elsevier
Alzheimer's disease (AD) is a complex disorder and the most common form of
neurodegenerative dementia. Several genetic, environmental, and physiological factors …

A meta-analysis of cytokines in Alzheimer's disease

W Swardfager, K Lanctôt, L Rothenburg, A Wong… - Biological …, 2010 - Elsevier
BACKGROUND: Studies suggest that inflammation is involved in the neurodegenerative
cascade leading to Alzheimer's disease (AD) pathology and symptoms. This study sought to …

Blood and CSF chemokines in Alzheimer's disease and mild cognitive impairment: a systematic review and meta-analysis

F Zhou, Y Sun, X **e, Y Zhao - Alzheimer's research & therapy, 2023 - Springer
Objective Chemokines, which are chemotactic inflammatory mediators involved in
controlling the migration and residence of all immune cells, are closely associated with brain …

Gut microbiota–driven brain Aβ amyloidosis in mice requires microglia

HB Dodiya, HL Lutz, IQ Weigle, P Patel… - Journal of Experimental …, 2022 - rupress.org
We previously demonstrated that lifelong antibiotic (ABX) perturbations of the gut
microbiome in male APPPS1-21 mice lead to reductions in amyloid β (Aβ) plaque pathology …

CXCR3 ligands in disease and therapy

K Van Raemdonck, PE Van den Steen… - Cytokine & growth factor …, 2015 - Elsevier
Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

The interleukin 1 alpha, interleukin 1 beta, interleukin 6 and alpha-2-macroglobulin serum levels in patients with early or late onset Alzheimer's disease, mild cognitive …

E Dursun, D Gezen-Ak, H Hanağası, B Bilgiç… - Journal of …, 2015 - Elsevier
Alzheimer's disease (EOAD, LOAD), mild cognitive impairment (MCI), Parkinson's disease
(PD) and healthy controls were included to determine the serum interleukin-1s (IL-1α, IL-1β) …

Chemokines and chemokine receptors in mood disorders, schizophrenia, and cognitive impairment: a systematic review of biomarker studies

MJ Stuart, BT Baune - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
The search for immune biomarkers in psychiatric disorders has primarily focused on pro-
inflammatory cytokines. Other immune proteins including chemokines have been relatively …

Circulating levels of IL-1 family cytokines and receptors in Alzheimer's disease: new markers of disease progression?

P Italiani, I Puxeddu, S Napoletano, E Scala… - Journal of …, 2018 - Springer
Background Although the mechanisms underlying AD neurodegeneration are not fully
understood, it is now recognised that inflammation could play a crucial role in the initiation …

High blood caffeine levels in MCI linked to lack of progression to dementia

C Cao, DA Loewenstein, X Lin… - Journal of …, 2012 - journals.sagepub.com
Although both human epidemiologic and animal model studies have suggested that
caffeine/coffee protects against Alzheimer's disease, direct human evidence for this premise …