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The roles of matrix metalloproteinases and their inhibitors in human diseases
Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM)
remodeling endopeptidases that have the capacity to degrade almost every component of …
remodeling endopeptidases that have the capacity to degrade almost every component of …
Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
C Li, YQ Ni, H Xu, QY **ang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …
Role of exosomal non-coding RNAs from tumor cells and tumor-associated macrophages in the tumor microenvironment
Z Xu, Y Chen, L Ma, Y Chen, J Liu, Y Guo, T Yu… - Molecular Therapy, 2022 - cell.com
Exosomes have a crucial role in intercellular communication and mediate interactions
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
between tumor cells and tumor-associated macrophages (TAMs). Exosome-encapsulated …
Effect of exosomal miRNA on cancer biology and clinical applications
Z Sun, K Shi, S Yang, J Liu, Q Zhou, G Wang, J Song… - Molecular cancer, 2018 - Springer
Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …
[HTML][HTML] Metalloproteinases and their inhibitors: potential for the development of new therapeutics
The metalloproteinase (MP) family of zinc-dependent proteases, including matrix
metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin …
metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin …
Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1
YL Hsu, JY Hung, WA Chang, YS Lin, YC Pan, PH Tsai… - Oncogene, 2017 - nature.com
Hypoxia plays a critical role during the evolution of malignant cells and tumour
microenvironment (TME). Tumour-derived exosomes contain informative microRNAs …
microenvironment (TME). Tumour-derived exosomes contain informative microRNAs …
TIMPs: versatile extracellular regulators in cancer
HW Jackson, V Defamie, P Waterhouse… - Nature Reviews …, 2017 - nature.com
A compelling long-term goal of cancer biology is to understand the crucial players during
tumorigenesis in order to develop new interventions. Here, we review how the four non …
tumorigenesis in order to develop new interventions. Here, we review how the four non …
Exosomes as miRNA carriers: formation–function–future
X Yu, M Odenthal, JWU Fries - International journal of molecular sciences, 2016 - mdpi.com
Exosomes, which are one of the smallest extracellular vesicles released from cells, have
been shown to carry different nucleic acids, including microRNAs (miRNAs). miRNAs …
been shown to carry different nucleic acids, including microRNAs (miRNAs). miRNAs …
Visualized SERS imaging of single molecule by Ag/black phosphorus nanosheets
C Lin, S Liang, Y Peng, L Long, Y Li, Z Huang… - Nano-micro letters, 2022 - Springer
Highlights Ag/BP-NS exhibit remarkable surface-enhanced Raman scattering performance
with single-molecule detection ability. This remarkable enhancement can be attributed to the …
with single-molecule detection ability. This remarkable enhancement can be attributed to the …
Hypoxia‐inducible exosomes facilitate liver‐tropic premetastatic niche in colorectal cancer
H Sun, Q Meng, C Shi, H Yang, X Li, S Wu… - …, 2021 - Wiley Online Library
Background and Aims Liver metastasis is a frequent occurrence in patients with colorectal
cancer (CRC), with 15%‐25% of CRC patients having liver metastases at the time of initial …
cancer (CRC), with 15%‐25% of CRC patients having liver metastases at the time of initial …