Computational flow dynamic analysis in left atrial appendage thrombus formation risk: A review

S Valvez, M Oliveira-Santos, AP Piedade… - Applied Sciences, 2023 - mdpi.com
Atrial fibrillation (AF) is a common cardiac arrhythmia characterized by irregular and rapid
electrical activity in the atria, leading to ineffective contraction and poor blood flow. More …

Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke

A Qureshi, GYH Lip, DA Nordsletten… - Frontiers in …, 2023 - frontiersin.org
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …

LAFlowNet: A dynamic graph method for the prediction of velocity and pressure fields in left atrium and left atrial appendage

X Liu, H Lin, X Liu, J Qian, S Cai, H Fan… - Engineering Applications of …, 2024 - Elsevier
The blood flow patterns within the left atrium (LA) and left atrial appendage (LAA) are crucial
for diagnosing and treating thrombosis and stroke. Although computational fluid dynamics …

Finding low CHA2DS2-VASc scores unreliable? Why not give morphological and hemodynamic methods a try?

YR Sun, Y Ling, Z Chen, Z Wang, T Li… - Frontiers in …, 2023 - frontiersin.org
Patients with atrial fibrillation (AF) suffer from a high risk of thrombosis. Currently, the
CHA2DS2-VASc score is the most widely used tool for risk stratification in patients with AF …

Patient-specific computational fluid dynamics for hypertrophic obstructive cardiomyopathy

Q Hou, W Wu, L Fang, X Zhang, C Sun, L Ji… - International Journal of …, 2023 - Elsevier
Background The heterogeneous morphologic and functional expression of hypertrophic
obstructive cardiomyopathy (HOCM) is evidenced by established imaging, multimodality …

Multiphase patient-specific simulations to study fibrillation-induced thrombosis in the left atrial appendage

A Bouchnita, V Volpert, N Kozulinas, AV Belyaev… - Physics of …, 2024 - pubs.aip.org
Thrombosis commonly develops in the left atrial appendage of patients with atrial fibrillation.
The formation of blood clots in atrial appendage is a complex process, which depends on …

Hemodynamic differences caused by left atrial appendage modeling contours

Y Chen, B Xu, Y Cheng, K Luo, J Fan, M **ang - Physics of Fluids, 2023 - pubs.aip.org
Comparing the hemodynamic parameters of thrombus-positive and thrombus-negative
patients in the early stages of the disease (before thrombus formation occurs) can help …

Personalized biomechanical insights in atrial fibrillation: opportunities & challenges

Å Telle, C Bargellini, Y Chahine… - Expert Review of …, 2023 - Taylor & Francis
Introduction Atrial fibrillation (AF) is an increasingly prevalent and significant worldwide
health problem. Manifested as an irregular atrial electrophysiological activation, it is …

Impact of left atrial wall motion assumptions in fluid simulations on proposed predictors of thrombus formation

HA Kjeldsberg, C Albors, J Mill… - International Journal …, 2024 - Wiley Online Library
Atrial fibrillation (AF) poses a significant risk of stroke due to thrombus formation, which
primarily occurs in the left atrial appendage (LAA). Medical image‐based computational fluid …

On the importance of fundamental computational fluid dynamics toward a robust and reliable model of left atrial flows

E Khalili, C Daversin‐Catty, AL Olivares… - International Journal …, 2024 - Wiley Online Library
Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated
level, for example, revealing plausible relationships between hemodynamics and stresses …