Relationship between microsatellite status and immune microenvironment of colorectal cancer and its application to diagnosis and treatment
J Bai, H Chen, X Bai - Journal of Clinical Laboratory Analysis, 2021 - Wiley Online Library
Due to advances in understanding the immune microenvironment of colorectal cancer
(CRC), microsatellite classification (dMMR/MSI‐H and pMMR/MSS) has become a key …
(CRC), microsatellite classification (dMMR/MSI‐H and pMMR/MSS) has become a key …
Few, but efficient: the role of mast cells in breast cancer and other solid tumors
MT Majorini, MP Colombo, D Lecis - Cancer Research, 2022 - AACR
Tumor outcome is determined not only by cancer cell–intrinsic features but also by the
interaction between cancer cells and their microenvironment. There is great interest in tumor …
interaction between cancer cells and their microenvironment. There is great interest in tumor …
Construction of TME and identification of crosstalk between malignant cells and macrophages by SPP1 in hepatocellular carcinoma
Liver cancer accounts for 6% of all malignancies causing death worldwide, and
hepatocellular carcinoma (HCC) is the most common histological type. HCC is a …
hepatocellular carcinoma (HCC) is the most common histological type. HCC is a …
Significance of RNA N6-methyladenosine regulators in the diagnosis and subtype classification of childhood asthma using the gene expression omnibus database
B Dai, F Sun, X Cai, C Li, H Liu, Y Shang - Frontiers in genetics, 2021 - frontiersin.org
RNA N6-methyladenosine (m6A) regulators play important roles in a variety of biological
functions. Nonetheless, the roles of m6A regulators in childhood asthma remain unknown. In …
functions. Nonetheless, the roles of m6A regulators in childhood asthma remain unknown. In …
[HTML][HTML] Analysis of the molecular nature associated with microsatellite status in colon cancer identifies clinical implications for immunotherapy
Background Microsatellite instability in colon cancer implies favorable therapeutic outcomes
after checkpoint blockade immunotherapy. However, the molecular nature of microsatellite …
after checkpoint blockade immunotherapy. However, the molecular nature of microsatellite …
A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer
X Bao, Q Li, D Chen, X Dai, C Liu, W Tian, H Zhang… - Cell Reports …, 2024 - cell.com
Colorectal cancer (CRC) is a common malignancy involving multiple cellular components.
The CRC tumor microenvironment (TME) has been characterized well at single-cell …
The CRC tumor microenvironment (TME) has been characterized well at single-cell …
5mC regulator-mediated molecular subtypes depict the hallmarks of the tumor microenvironment and guide precision medicine in bladder cancer
Background Depicting the heterogeneity and functional characteristics of the tumor
microenvironment (TME) is necessary to achieve precision medicine for bladder cancer …
microenvironment (TME) is necessary to achieve precision medicine for bladder cancer …
DeSide: A unified deep learning approach for cellular deconvolution of tumor microenvironment
Cellular deconvolution via bulk RNA sequencing (RNA-seq) presents a cost-effective and
efficient alternative to experimental methods such as flow cytometry and single-cell RNA-seq …
efficient alternative to experimental methods such as flow cytometry and single-cell RNA-seq …
Effect of M6A regulators on diagnosis, subtype classification, prognosis and novel therapeutic target development of idiopathic pulmonary fibrosis
G Huang, S Huang, H Cui - Frontiers in Pharmacology, 2022 - frontiersin.org
Molecular biology studies show that RNA N6-methyladenosine (m6A) modifications may
take part in the incidence and development of idiopathic pulmonary fibrosis (IPF) …
take part in the incidence and development of idiopathic pulmonary fibrosis (IPF) …
Immune landscape and a promising immune prognostic model associated with TP53 in early‐stage lung adenocarcinoma
C Wu, X Rao, W Lin - Cancer Medicine, 2021 - Wiley Online Library
Purpose TP53 mutation, one of the most frequent mutations in early‐stage lung
adenocarcinoma (LUAD), triggers a series of alterations in the immune landscape …
adenocarcinoma (LUAD), triggers a series of alterations in the immune landscape …