The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the
development of lipid nanoparticle delivery systems that not only efficiently express the …

Extracellular vesicles (EVs) are natural nanoparticles containing biologically active
molecules. They are important mediators of intercellular communication and can be …

Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells
assembles large complexes called inflammasomes, which activate inflammatory caspases …

Middle East respiratory syndrome coronavirus (MERS-CoV) is the causative agent of a
severe respiratory disease associated with more than 2468 human infections and over 851 …

Clinical studies suggest the therapeutic potential of psychedelics, including ayahuasca,
DMT, psilocybin, and LSD, in stress-related disorders. These substances induce cognitive …

Despite the success of the BNT162b2 mRNA vaccine, the immunological mechanisms that
underlie its efficacy are poorly understood. Here we analyzed the innate and adaptive …

Epilepsy is one of the most common and disabling chronic neurological disorders.
Antiseizure medications (ASMs), previously referred to as anticonvulsant or antiepileptic …

Engineering chimeric antigen receptors (CAR) or T cell receptors (TCR) helps create
disease-specific T cells for targeted therapy, but the cost and rigor associated with …

Adoptive cell therapy (ACT) has proven to be highly effective in treating blood cancers, but
traditional approaches to ACT are poorly effective in treating solid tumors observed …

Ketamine, a racemic mixture of (S)-ketamine and (R)-ketamine enantiomers, has been used
as an anesthetic, analgesic and more recently, as an antidepressant. However, ketamine …