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Review of applications of high-throughput sequencing in personalized medicine: barriers and facilitators of future progress in research and clinical application
There has been an exponential growth in the performance and output of sequencing
technologies (omics data) with full genome sequencing now producing gigabases of reads …
technologies (omics data) with full genome sequencing now producing gigabases of reads …
Reconfiguring the bioinformatics computational spectrum: Challenges and opportunities of fpga-based bioinformatics acceleration platforms
This paper conducts a detailed survey on the use of FPGA-based reconfigurable computing
platforms for a wide range of sequence and structural bioinformatics applications, with …
platforms for a wide range of sequence and structural bioinformatics applications, with …
AIM: accelerating computational genomics through scalable and noninvasive accelerator-interposed memory
Computational genomics plays an important role in health care, but is computationally
challenging as most genomics applications use large data sets and are both computation …
challenging as most genomics applications use large data sets and are both computation …
FPGA-based hardware accelerator for an embedded factor graph with configurable optimization
A factor graph (FG) can be considered as a unified model combining a Bayesian network
(BN) and a Markov random field (MRF). The inference mechanism of a FG can be used to …
(BN) and a Markov random field (MRF). The inference mechanism of a FG can be used to …
WImpiBLAST: Web interface for mpiBLAST to help biologists perform large-scale annotation using high performance computing
The function of a newly sequenced gene can be discovered by determining its sequence
homology with known proteins. BLAST is the most extensively used sequence analysis …
homology with known proteins. BLAST is the most extensively used sequence analysis …
ACA-SDS: Adaptive crypto acceleration for secure data storage in big data
In the era of big data, the demand for secure data storage is rapidly increasing. To
accelerate the complex encryption computation, both specific instructions and hardware …
accelerate the complex encryption computation, both specific instructions and hardware …
GPU technology as a platform for accelerating local complexity analysis of protein sequences
A Papadopoulos, I Kirmitzoglou… - 2013 35th Annual …, 2013 - ieeexplore.ieee.org
The use of GPGPU programming paradigm (running CUDA-enabled algorithms on GPU
cards) in Bioinformatics showed promising results [1]. As such a similar approach can be …
cards) in Bioinformatics showed promising results [1]. As such a similar approach can be …
Custom hardware versus cloud computing in big data
The computational and data handling challenges in big data are immense yet a market is
steadily growing traditionally supported by technologies such as Hadoop for management …
steadily growing traditionally supported by technologies such as Hadoop for management …
Modular design of a factor-graph-based inference engine on a System-On-Chip (SoC)
Factor graphs are probabilistic graphical frameworks for modeling complex and dynamic
systems. They can be used in a broad range of application domains, from machine learning …
systems. They can be used in a broad range of application domains, from machine learning …