Soft tissue tumors are a relatively rare and diagnostically challenging group of neoplasms
that can have varying lines of differentiation. Accurate diagnosis is important for appropriate …

The fifth edition of the World Health Organization (WHO) classification of soft tissue and
bone tumours was published in May 2020. This 'Blue Book', which is also available digitally …

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and
represents a high-grade neoplasm of skeletal myoblast-like cells. Decades of clinical and …

Sarcoma represents a highly heterogeneous group of tumours. We report here the first
unbiased and systematic search for gene fusions combined with unsupervised expression …

Rhabdomyosarcomas comprise the single largest category of soft tissue sarcomas in
children and adolescents in the United States, occurring in 4.5 million people aged below 20 …

Sclerosing and spindle cell rhabdomyosarcoma is a rare histologic subtype, designated in
the latest WHO classification as a stand-alone pathologic entity. Three genomic groups have …

Rhabdomyosarcomas are malignancies associated with a rhabdomyoblastic phenotype
which can be demonstrated morphologically or by immunohistochemistry for MYOD1 and …

Soft tissue undifferentiated round cell sarcoma (URCS) occurring in infants is a
heterogenous group of tumors, often lacking known genetic abnormalities. On the basis of at …

Aims Infantile fibrosarcoma is characterised by intersecting fascicles of spindle cells and
ETV 6–NTRK 3 gene fusion in most cases. Given histological overlap with other spindle‐cell …

Rhabdomyosarcomas with TFCP2 fusions represent an emerging subtype of tumors, initially
discovered by RNA-sequencing. We report herein the clinicopathological, transcriptional …