Mucosal vaccines—fortifying the frontiers

EC Lavelle, RW Ward - Nature Reviews Immunology, 2022 - nature.com
Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …

[HTML][HTML] Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

COVID-19 vaccine development and a potential nanomaterial path forward

MD Shin, S Shukla, YH Chung, V Beiss… - Nature …, 2020 - nature.com
The COVID-19 pandemic has infected millions of people with no clear signs of abatement
owing to the high prevalence, long incubation period and lack of established treatments or …

Nanotechnology for COVID-19: therapeutics and vaccine research

G Chauhan, MJ Madou, S Kalra, V Chopra, D Ghosh… - ACS …, 2020 - ACS Publications
The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …

Liposome-based delivery of biological drugs

KT Magar, GF Boafo, X Li, Z Chen, W He - Chinese Chemical Letters, 2022 - Elsevier
Biological drugs are attracting tremendous attention in disease treatment. However, their
application is significantly limited by their inherent properties, such as high hydrophilicity …

Microneedles for painless transdermal immunotherapeutic applications

H Amani, MA Shahbazi, C D'Amico, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …

Vaccine therapies for cancer: then and now

MA Morse, WR Gwin III, DA Mitchell - Targeted oncology, 2021 - Springer
There are strong biologic and preclinical rationales for the development of therapeutic
cancer vaccines; however, the clinical translation of this treatment strategy has been …

[HTML][HTML] Progress towards the development of a universal influenza vaccine

WC Wang, EE Sayedahmed, S Sambhara, SK Mittal - Viruses, 2022 - mdpi.com
Influenza viruses are responsible for millions of cases globally and significantly threaten
public health. Since pandemic and zoonotic influenza viruses have emerged in the last 20 …

Advances in gene-based vaccine platforms to address the COVID-19 pandemic

D Pushparajah, S Jimenez, S Wong, H Alattas… - Advanced drug delivery …, 2021 - Elsevier
The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus
2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan …

Nano-biotechnology, an applicable approach for sustainable future

N Shahcheraghi, H Golchin, Z Sadri, Y Tabari… - 3 Biotech, 2022 - Springer
Nanotechnology is one of the most emerging fields of research within recent decades and is
based upon the exploitation of nano-sized materials (eg, nanoparticles, nanotubes …