The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …

Background The Hierarchical Taxonomy of Psychopathology (HiTOP) is a classification
system that seeks to organize psychopathology using quantitative evidence–yet the current …

In this article, we describe the collaborative process that is underway to develop measures
for the Hierarchical Taxonomy of Psychopathology (HiTOP). The HiTOP model has …

A main goal in translational neuroscience is to identify neural correlates of psychopathology
(“biomarkers”) that can be used to facilitate diagnosis, prognosis, and treatment. This goal …

Obsessive-compulsive symptoms are frequent in schizophrenia-spectrum disorders and
often cause differential diagnostic challenges, especially in first-contact patients. Drawing …

Seduced by their mathematical beauty, psychologists have been using latent variable
models for more than a century. Whether discussing a general factor of cognitive ability …

Background Psychopathology has been long recognized as a fluctuating process with
various expressions over time, which can only be properly understood if we follow …

Quantitative, empirical approaches to establishing the structure of psychopathology hold
promise to improve on traditional psychiatric classification systems. The Hierarchical …

BackgroundDespite statistical evidence of a general factor of psychopathology (ie, p-factor),
there is little agreement about what the p-factor represents. Researchers have proposed five …

Abstract The Hierarchical Taxonomy of Psychopathology (HiTOP) arranges phenotypes of
mental disorders based on empirical covariation, ranging from narrowly defined symptoms …