Heart failure (HF) is a rapidly growing public health issue with an estimated prevalence of 64
million people globally. Although the incidence of HF has stabilised worldwide and seems to …

Paravalvular regurgitation (PVR) is a frequent complication of transcatheter aortic valve
replacement that has been shown to be associated with increased mortality. The objective of …

Aims In patients with aortic stenosis (AS), risk stratification for aortic valve replacement
(AVR) relies mainly on valve-related factors, symptoms and co-morbidities. We sought to …

Valvular disease remains a major cause of cardiovascular morbidity and mortality
worldwide. 1 Over the past decade, catheter-based interventions in valvular disease have …

Background We compared transcatheter aortic-valve replacement (TAVR), using a self-
expanding transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in …

Objectives: This study sought to evaluate the safety and efficacy of the CoreValve
transcatheter heart valve (THV) for the treatment of severe aortic stenosis in patients at …

Background The impact of aortic valve replacement (AVR) on progression/regression of
extravalvular cardiac damage and its association with subsequent prognosis is unknown …

Aim The impact of paravalvular regurgitation (PVR) following transcatheter aortic valve
replacement (TAVR) remains uncertain. In this analysis, we sought to evaluate the impact of …

Background: Little is known about the incidence of prosthesis-patient mismatch (PPM) and
its impact on outcomes after transcatheter aortic valve replacement (TAVR). Objectives: The …

Background—The higher risk of adverse outcomes after transapical (TA) versus
transfemoral (TF) transcatheter aortic valve replacement (TAVR) could be attributable to TA …