Computational psychiatry: from synapses to sentience

K Friston - Molecular psychiatry, 2023 - nature.com
This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …

Computational psychiatry: the brain as a phantastic organ

KJ Friston, KE Stephan, R Montague… - The Lancet Psychiatry, 2014 - thelancet.com
In this Review, we discuss advances in computational neuroscience that relate to psychiatry.
We review computational psychiatry in terms of the ambitions of investigators, emerging …

The computational anatomy of psychosis

RA Adams, KE Stephan, HR Brown, CD Frith… - Frontiers in …, 2013 - frontiersin.org
This paper considers psychotic symptoms in terms of false inferences or beliefs. It is based
on the notion that the brain is an inference machine that actively constructs hypotheses to …

Computational psychiatry: towards a mathematically informed understanding of mental illness

RA Adams, QJM Huys, JP Roiser - Journal of Neurology …, 2016 - jnnp.bmj.com
Computational Psychiatry aims to describe the relationship between the brain's
neurobiology, its environment and mental symptoms in computational terms. In so doing, it …

Advances in the computational understanding of mental illness

QJM Huys, M Browning, MP Paulus… - …, 2021 - nature.com
Computational psychiatry is a rapidly growing field attempting to translate advances in
computational neuroscience and machine learning into improved outcomes for patients …

Computational approaches to psychiatry

KE Stephan, C Mathys - Current opinion in neurobiology, 2014 - Elsevier
Highlights•We summarize recent progress in computational and physiological
models.•These advances provide a basis for future diagnostic applications in psychiatry.•A …

Active inference and agency: optimal control without cost functions

K Friston, S Samothrakis, R Montague - Biological cybernetics, 2012 - Springer
This paper describes a variational free-energy formulation of (partially observable) Markov
decision problems in decision making under uncertainty. We show that optimal control can …

Circular inferences in schizophrenia

R Jardri, S Deneve - Brain, 2013 - academic.oup.com
A considerable number of recent experimental and computational studies suggest that
subtle impairments of excitatory to inhibitory balance or regulation are involved in many …

[HTML][HTML] Bayesian inferences about the self (and others): A review

M Moutoussis, P Fearon, W El-Deredy, RJ Dolan… - Consciousness and …, 2014 - Elsevier
Viewing the brain as an organ of approximate Bayesian inference can help us understand
how it represents the self. We suggest that inferred representations of the self have a …

Compulsivity and impulsivity traits linked to attenuated developmental frontostriatal myelination trajectories

G Ziegler, TU Hauser, M Moutoussis, ET Bullmore… - Nature …, 2019 - nature.com
The transition from adolescence to adulthood is a period when ongoing brain development
coincides with a substantially increased risk of psychiatric disorders. The developmental …