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Intramedullary nailing is the preferred method for treating fractures of the femoral shaft. The
piriformis fossa and greater trochanter are viable starting points for antegrade nailing …

Objectives: The timing of definitive fixation for major fractures in patients with multiple
injuries is controversial. To address this gap, we randomized patients with blunt multiple …

Background: Platelet-rich plasma (PRP) and bone marrow concentrate (BMC) are
orthobiologic therapies with numerous growth factors and other bioactive molecules. Before …

Background: Although early fracture fixation is expedient in patients with multiple injuries,
early total care (ETC) may be associated with posttraumatic systemic complications. This …

The management of open fractures continues to provide challenges for the orthopedic
surgeon. Despite the improvements in technology and surgical techniques, rates of infection …

Purpose Much research is now being conducted in order to understand the role of cytokines
in the development of the inflammatory response following trauma. The purpose of this study …

The principles of fracture management in patients with multiple injuries continue to be of
crucial importance. Early treatment of unstable polytraumatized patients with head, chest …

Open fractures are complex injuries associated with high morbidity and mortality. Despite
advances made in fracture care and infection prevention, open fractures remain a …

Open fractures are associated with an increased risk of infection and healing complications.
Management of open fractures is based on the following principles: assessment of the …