Curvature in biological systems: its quantification, emergence, and implications across the scales

B Schamberger, R Ziege, K Anselme… - advanced …, 2023 - Wiley Online Library
Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

Mechanochemical feedback loops in development and disease

E Hannezo, CP Heisenberg - Cell, 2019 - cell.com
There is increasing evidence that both mechanical and biochemical signals play important
roles in development and disease. The development of complex organisms, in particular …

Polyamide membranes with nanoscale Turing structures for water purification

Z Tan, S Chen, X Peng, L Zhang, C Gao - Science, 2018 - science.org
The emergence of Turing structures is of fundamental importance, and designing these
structures and develo** their applications have practical effects in chemistry and biology …

Hair-bearing human skin generated entirely from pluripotent stem cells

J Lee, CC Rabbani, H Gao, MR Steinhart, BM Woodruff… - Nature, 2020 - nature.com
The skin is a multilayered organ, equipped with appendages (that is, follicles and glands),
that is critical for regulating body temperature and the retention of bodily fluids, guarding …

Paired-cell sequencing enables spatial gene expression map** of liver endothelial cells

KB Halpern, R Shenhav, H Massalha, B Toth… - Nature …, 2018 - nature.com
Spatially resolved single-cell RNA sequencing (scRNAseq) is a powerful approach for
inferring connections between a cell's identity and its position in a tissue. We recently …

MorphoGraphX: A platform for quantifying morphogenesis in 4D

P Barbier de Reuille, AL Routier-Kierzkowska… - elife, 2015 - elifesciences.org
Morphogenesis emerges from complex multiscale interactions between genetic and
mechanical processes. To understand these processes, the evolution of cell shape …

[HTML][HTML] Positional information and reaction-diffusion: two big ideas in developmental biology combine

J Green, J Sharpe - Development, 2015 - journals.biologists.com
One of the most fundamental questions in biology is that of biological pattern: how do the
structures and shapes of organisms arise? Undoubtedly, the two most influential ideas in …

Diffusiophoresis-enhanced Turing patterns

BM Alessio, A Gupta - Science Advances, 2023 - science.org
Turing patterns are fundamental in biophysics, emerging from short-range activation and
long-range inhibition processes. However, their paradigm is based on diffusive transport …

Reaction-diffusion model as a framework for understanding biological pattern formation

S Kondo, T Miura - science, 2010 - science.org
The Turing, or reaction-diffusion (RD), model is one of the best-known theoretical models
used to explain self-regulated pattern formation in the develo** animal embryo. Although …

Cytosystems dynamics in self-organization of tissue architecture

Y Sasai - Nature, 2013 - nature.com
Our knowledge of the principles by which organ architecture develops through complex
collective cell behaviours is still limited. Recent work has shown that the shape of such …