Biocatalysis, using defined enzymes for organic transformations, has become a common
tool in organic synthesis, which is also frequently applied in industry. The generally high …

Aromatics and their derivatives are valuable chemicals with a plethora of important
applications and thus play an integral role in modern society. Their current production relies …

The Friedel–Crafts (F–C) reaction has been a fundamental pillar of both academic and
industrial synthetic organic chemistry since its discovery in 1873. Its success is based on the …

Plant-beneficial Pseudomonas spp. aggressively colonize the rhizosphere and produce
numerous secondary metabolites, such as 2, 4-diacetylphloroglucinol (DAPG). DAPG is a …

Friedel‐Crafts alkylation and acylation reactions are important methodologies in synthetic
and industrial chemistry for the construction of aryl‐alkyl and aryl‐acyl linkages that are …

Pseudomonas protegens Pf-5 is an effective biocontrol agent that protects many crops
against pathogens, including the fungal pathogen Botrytis cinerea causing gray mold …

Streptococcus mutans is a common constituent of dental plaque and a major etiologic agent
of dental caries (tooth decay). In this study, we elucidated the biosynthetic pathway encoded …

Friedel–Crafts acylation (FCA) is a highly beneficial approach in organic chemistry for
creating the important C–C bonds that are necessary for building intricate frameworks …

Herpotrichones A and B (1 and 2), two intermolecular [4+ 2] adducts with an unprecedented
pentacyclic 6/6/6/6/3 skeleton, were isolated from Herpotrichia sp. SF09, an isopod …

Shikonin is a natural naphthoquinone derivative that specifically occurs in boraginaceous
plants, and the major active ingredient of the medicinal plant Lithospermum erythrorhizon …