Advance computational tools for multiomics data learning
The burgeoning field of bioinformatics has seen a surge in computational tools tailored for
omics data analysis driven by the heterogeneous and high-dimensional nature of omics …
omics data analysis driven by the heterogeneous and high-dimensional nature of omics …
Circular RNAs and RNA splice variants as biomarkers for prognosis and therapeutic response in the liquid biopsies of lung cancer patients
F De Fraipont, S Gazzeri, WC Cho, B Eymin - Frontiers in genetics, 2019 - frontiersin.org
Lung cancer, including non-small cell lung carcinoma (NSCLC), is the most frequently
diagnosed cancer. It is also the leading cause of cancer-related mortality worldwide …
diagnosed cancer. It is also the leading cause of cancer-related mortality worldwide …
[HTML][HTML] Robustness of differential gene expression analysis of RNA-seq
Abstract RNA-sequencing (RNA-seq) is a relatively new technology that lacks
standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis …
standardisation. RNA-seq can be used for Differential Gene Expression (DGE) analysis …
Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth
Identification of pregnancies at risk of preterm birth (PTB), the leading cause of newborn
deaths, remains challenging given the syndromic nature of the disease. We report a …
deaths, remains challenging given the syndromic nature of the disease. We report a …
Differential gene expression in disease: a comparison between high-throughput studies and the literature
R Rodriguez-Esteban, X Jiang - BMC medical genomics, 2017 - Springer
Background Differential gene expression is important to understand the biological
differences between healthy and diseased states. Two common sources of differential gene …
differences between healthy and diseased states. Two common sources of differential gene …
Splicing factor ESRP1 controls ER‐positive breast cancer by altering metabolic pathways
The epithelial splicing regulatory proteins 1 and 2 (ESRP 1 and ESRP 2) control the
epithelial‐to‐mesenchymal transition (EMT) splicing program in cancer. However, their role …
epithelial‐to‐mesenchymal transition (EMT) splicing program in cancer. However, their role …
Identification of potential biomarkers related to glioma survival by gene expression profile analysis
JBK Hsu, TH Chang, GA Lee, TY Lee, CY Chen - BMC medical genomics, 2019 - Springer
Background Recent studies have proposed several gene signatures as biomarkers for
different grades of gliomas from various perspectives. However, most of these genes can …
different grades of gliomas from various perspectives. However, most of these genes can …
Transcriptomics for clinical and experimental biology research: hang on a seq
Sequencing the human genome empowers translational medicine, facilitating transcriptome‐
wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are …
wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are …
Machine learning approaches to predict lupus disease activity from gene expression data
The integration of gene expression data to predict systemic lupus erythematosus (SLE)
disease activity is a significant challenge because of the high degree of heterogeneity …
disease activity is a significant challenge because of the high degree of heterogeneity …
[HTML][HTML] Probing infectious disease by single-cell RNA sequencing: Progresses and perspectives
G Luo, Q Gao, S Zhang, B Yan - Computational and Structural …, 2020 - Elsevier
The increasing application of single-cell RNA sequencing (scRNA-seq) technology in life
science and biomedical research has significantly increased our understanding of the …
science and biomedical research has significantly increased our understanding of the …