The concept of phase-separation-mediated formation of biomolecular condensates provides
a new framework to understand cellular organization and cooperativity-dependent cellular …

Proteins and synthetic polymers can undergo phase transitions in response to changes to
intensive solution parameters such as temperature, proton chemical potentials (pH), and …

INTRODUCTION Liquid-liquid phase separation of biopolymers has emerged as a driving
force for assembling membraneless biomolecular condensates. Despite substantial …

Elastin-like polypeptides (ELPs) are a class of stimuli-responsive biopolymers inspired by
the intrinsically disordered domains of tropoelastin that are composed of repeats of the …

Upon stress challenges, proteins/RNAs undergo liquid–liquid phase separation (LLPS) to
fine-tune cell physiology and metabolism to help cells adapt to adverse environments. The …

Elastin-like polypeptides (ELPs) are biopolymers inspired by human elastin. Their lower
critical solution temperature phase transition behavior and biocompatibility make them …

Elastin-like polypeptides (ELPs) are stimulus-responsive peptide polymers that exhibit
inverse temperature phase transition behavior, causing an ELP to aggregate above its …

The inclusion of microexons by alternative splicing occurs frequently in neuronal proteins.
The roles of these sequences are largely unknown, and changes in their degree of inclusion …

Most nanocarriers possess low drug loading, resulting in frequently repeated administration
and thereby high cost and increased side effects. Furthermore, the characteristics of …

To realize the full potential of emerging nucleic acid therapies, there is a need for effective
delivery agents to transport cargo to cells of interest. Protein materials exhibit several unique …