Physiology and diseases of tissue-resident macrophages

T Lazarov, S Juarez-Carreño, N Cox, F Geissmann - Nature, 2023‏ - nature.com
Embryo-derived tissue-resident macrophages are the first representatives of the
haematopoietic lineage to emerge in metazoans. In mammals, resident macrophages …

Inflammation in osteoarthritis: the latest progress and ongoing challenges

AJ Knights, SJ Redding, T Maerz - Current opinion in …, 2023‏ - journals.lww.com
Osteoarthritis is a debilitating chronic disease that manifests with widely varying
symptomatology. Inflammation is now appreciated as a key pathophysiological process in …

Exopolysaccharides from probiotic bacteria and their health potential

J Angelin, M Kavitha - International journal of biological macromolecules, 2020‏ - Elsevier
Exopolysaccharides (EPS) are extracellular macromolecules excreted as tightly bound
capsule or loosely attached slime layer in microorganisms. They play most prominent role …

Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight

BT Tierney, JK Kim, EG Overbey, KA Ryon, J Foox… - Nature …, 2024‏ - nature.com
Maintenance of astronaut health during spaceflight will require monitoring and potentially
modulating their microbiomes. However, documenting microbial shifts during spaceflight has …

Nonclassical monocytes in health and disease

PB Narasimhan, P Marcovecchio… - Annual review of …, 2019‏ - annualreviews.org
Monocytes are innate blood cells that maintain vascular homeostasis and are early
responders to pathogens in acute infections. There are three well-characterized classes of …

The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022‏ - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

[HTML][HTML] The main bioactive compounds of Scutellaria baicalensis Georgi. for alleviation of inflammatory cytokines: A comprehensive review

H Liao, J Ye, L Gao, Y Liu - Biomedicine & Pharmacotherapy, 2021‏ - Elsevier
Scutellaria baicalensis Georgi., a plant used in traditional Chinese medicine, has multiple
biological activities, including anti-inflammatory, antiviral, antitumor, antioxidant, and …

Aseptic and septic prosthetic joint loosening: Impact of biomaterial wear on immune cell function, inflammation, and infection

NA Hodges, EM Sussman, JP Stegemann - Biomaterials, 2021‏ - Elsevier
The success of total joint replacements has led to consistent growth in the use of arthroplasty
in progressively younger patients. However, more than 10 percent of patients require …

GM-CSF: from growth factor to central mediator of tissue inflammation

B Becher, S Tugues, M Greter - Immunity, 2016‏ - cell.com
The granulocyte-macrophage colony-stimulating factor (GM-CSF) was initially classified as a
hematopoietic growth factor. However, unlike its close relatives macrophage CSF (M-CSF) …

From monocytes to M1/M2 macrophages: phenotypical vs. functional differentiation

P Italiani, D Boraschi - Frontiers in immunology, 2014‏ - frontiersin.org
Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …