Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Macrophages are important components of the immune system. Mature macrophages can
be recruited to tumor microenvironment that affect tumor cell proliferation, invasion and …

This mini-review summarizes the current evidence for the role of macrophage activation and
polarization in inflammation and immune response pertinent to interstitial lung disease …

Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

Classically activated M1 macrophages and alternatively activated M2 macrophages are two
polarized subsets of macrophages at the extreme ends of a constructed continuum. In the …

Tumor-associated macrophages (TAMs) play a pivotal role in the progression and
resistance of tumors to different anticancer drugs. TAMs can modulate the tumor …

Macrophage is the key innate immune effector in first-line defense against the pathogens,
and can be polarized into different phenotypes to regulate a variety of immunological …

Background Periodontitis is a complicated inflammatory disease that damages the tooth-
supporting tissues, with limited pharmacotherapy available. Macrophage-targeting therapy …

Keloid refers to a fibroproliferative disorder characterized by an accumulation of extracellular
matrix (ECM) components at the dermis level, overgrowth beyond initial wound, and …