Major depressive disorder is a common psychiatric disorder associated with marked
suffering, morbidity, mortality, and cost. The World Health Organization projects that by 2030 …

Despite decades of research aimed at identifying the causes of postpartum depression
(PPD), PPD remains common, and the causes are poorly understood. Many have attributed …

OBJECTIVE: Most research on the effects of severe psychological stress has focused on
stress-related psychopathology. Here, the author develops psychobiological models of …

This review discusses neurobiological and psychosocial factors associated with stress-
induced depression and compares these factors with those believed to characterize stress …

In adulthood, twice as many women as men are depressed, a pattern that holds in most
nations. In childhood, girls are no more depressed than boys, but more girls than boys are …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

DHEA and DHEAS are steroids synthesized in human adrenals, but their function is unclear.
In addition to adrenal synthesis, evidence also indicates that DHEA and DHEAS are …

This chapter provides an overview of neurosteroids, especially their impact on the brain, sex
differences and their therapeutic potentials. Neurosteroids are synthesized within the brain …

The bark and/or seed cones of the Magnolia tree have been used in traditional herbal
medicines in Korea, China and Japan. Bioactive ingredients such as magnolol, honokiol, 4 …

Millions of people around the world suffer from psychiatric illnesses, causing unbearable
burden and immense distress to patients and their families. Accumulating evidence …