Global prevalence and clinical characteristics of metabolic-associated fatty liver disease: a meta-analysis and systematic review of 10 739 607 individuals

KE Chan, TJL Koh, ASP Tang, J Quek… - The Journal of …, 2022 - academic.oup.com
Abstract Background and Aims Metabolic-associated fatty liver disease (MAFLD) was
proposed as a better definition of nonalcoholic fatty liver disease (NAFLD) to encompass the …

Resmetirom, the first approved drug for the management of metabolic dysfunction-associated steatohepatitis: trials, opportunities, and challenges

M Kokkorakis, C Boutari, MA Hill… - Metabolism …, 2024 - metabolismjournal.com
Over the past decade, there have been several guideline updates for the diagnosis and
management of non-alcoholic fatty liver disease (NAFLD), which is the most common …

An international multidisciplinary consensus statement on MAFLD and the risk of CVD

XD Zhou, G Targher, CD Byrne, V Somers… - Hepatology …, 2023 - Springer
Background Fatty liver disease in the absence of excessive alcohol consumption is an
increasingly common condition with a global prevalence of~ 25–30% and is also associated …

An observational data meta-analysis on the differences in prevalence and risk factors between MAFLD vs NAFLD

GEH Lim, A Tang, CH Ng, YH Chin, WH Lim… - Clinical …, 2023 - Elsevier
Background & Aims The shift to redefine nonalcoholic fatty liver disease (NAFLD) as
metabolic associated fatty liver disease (MAFLD) can profoundly affect patient care, health …

Obesity and diabetes

C Boutari, A DeMarsilis, CS Mantzoros - Diabetes Research and Clinical …, 2023 - Elsevier
Obesity, which has currently reached pandemic dimensions, is usually accompanied by
diabetes mellitus type 2 (T2DM). These two conditions share common pathophysiological …

From non-alcoholic fatty liver disease (NAFLD) to steatotic liver disease (SLD): an ongoing journey towards refining the terminology for this prevalent metabolic …

M Kokkorakis, C Boutari, N Katsiki… - Metabolism-Clinical …, 2023 - metabolismjournal.com
Non-alcoholic fatty liver disease (NAFLD) is a prevalent metabolic condition closely
associated with genetic predisposition and/or obesity, lipodystrophy, and insulin resistance …

Metabolic associated fatty liver disease increases the risk of systemic complications and mortality. A meta-analysis and systematic review of 12 620 736 individuals

J Quek, CH Ng, ASP Tang, N Chew, M Chan… - Endocrine Practice, 2022 - Elsevier
Objective The recent introduction of the term metabolic associated fatty liver disease
(MAFLD) sought to reclassify nonalcoholic fatty liver disease (NAFLD). MAFLD is thought to …

Metabolic dysfunction-associated fatty liver disease: current therapeutic strategies

K Al Hashmi, RV Giglio, A Pantea Stoian… - Frontiers in …, 2024 - frontiersin.org
The definition of “Metabolic Associated Fatty Liver Disease–MAFLD” has replaced the
previous definition of Nonalcoholic Fatty Liver Disease (NAFLD), because cardiometabolic …

Severity and Remission of Metabolic Dysfunction–Associated Fatty/Steatotic Liver Disease With Chronic Kidney Disease Occurrence

J Gao, Y Li, Y Zhang, X Zhan, X Tian, J Li… - Journal of the …, 2024 - ahajournals.org
Background The association of the severity of hepatic steatosis in metabolic dysfunction–
associated fatty liver disease (MAFLD)/metabolic dysfunction–associated steatotic liver …

Statins' efficacy in non-alcoholic fatty liver disease: A systematic review and meta-analysis

C Boutari, PD Pappas, D Anastasilakis, CS Mantzoros - Clinical Nutrition, 2022 - Elsevier
Background & aims Non-alcoholic fatty liver disease (NAFLD) is closely related with the
metabolic syndrome and cardiovascular disease. Currently there is no approved medication …