Epidemiology of and diagnostic strategies for toxoplasmosis
F Robert-Gangneux, ML Dardé - Clinical microbiology reviews, 2012 - Am Soc Microbiol
The apicomplexan parasite Toxoplasma gondii was discovered a little over 100 years ago,
but knowledge of its biological life cycle and its medical importance has grown in the last 40 …
but knowledge of its biological life cycle and its medical importance has grown in the last 40 …
Treatment of toxoplasmosis: historical perspective, animal models, and current clinical practice
IR Dunay, K Gajurel, R Dhakal… - Clinical microbiology …, 2018 - Am Soc Microbiol
Primary Toxoplasma gondii infection is usually subclinical, but cervical lymphadenopathy or
ocular disease can be present in some patients. Active infection is characterized by …
ocular disease can be present in some patients. Active infection is characterized by …
Modulation of innate immunity by Toxoplasma gondii virulence effectors
Toxoplasma gondii is a common parasite of animals and humans and can cause serious
opportunistic infections. However, the majority of infections are asymptomatic, possibly …
opportunistic infections. However, the majority of infections are asymptomatic, possibly …
Toxoplasma Effectors Targeting Host Signaling and Transcription
Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
Using a model of lethal oral infection with Toxoplasma gondii, we examined the fate of both
induced and natural regulatory T (Treg) cells in the face of strong inflammatory responses …
induced and natural regulatory T (Treg) cells in the face of strong inflammatory responses …
Biological functions of tumor necrosis factor cytokines and their receptors
K Pfeffer - Cytokine & growth factor reviews, 2003 - Elsevier
Tumor necrosis factor (TNF; formerly known as TNFα) and lymphotoxin (LT) α, originally
characterized by their ability to induce tumor cell apoptosis and cachexia, are now …
characterized by their ability to induce tumor cell apoptosis and cachexia, are now …
Gr1+ inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii
The enteric pathogen Toxoplasma gondii is controlled by a vigorous innate T helper 1 (Th1)
cell response in the murine model. We demonstrated that after oral infection, the parasite …
cell response in the murine model. We demonstrated that after oral infection, the parasite …
Influence of the Host and Parasite Strain on the Immune Response During Toxoplasma Infection
Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host
range, including humans, across the globe. The outcome of infection differs remarkably …
range, including humans, across the globe. The outcome of infection differs remarkably …
Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii
MM Heimesaat, S Bereswill, A Fischer… - The Journal of …, 2006 - journals.aai.org
Oral infection of susceptible mice with Toxoplasma gondii results in Th1-type
immunopathology in the ileum. We investigated gut flora changes during ileitis and …
immunopathology in the ileum. We investigated gut flora changes during ileitis and …
Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation
S Bereswill, M Muñoz, A Fischer, R Plickert, LM Haag… - PloS one, 2010 - journals.plos.org
Background The health beneficial effects of Resveratrol, Curcumin and Simvastatin have
been demonstrated in various experimental models of inflammation. We investigated the …
been demonstrated in various experimental models of inflammation. We investigated the …