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Neurocognitive functioning in individuals at clinical high risk for psychosis: a systematic review and meta-analysis
Importance Neurocognitive functioning is a potential biomarker to advance detection,
prognosis, and preventive care for individuals at clinical high risk for psychosis (CHR-P) …
prognosis, and preventive care for individuals at clinical high risk for psychosis (CHR-P) …
European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia
Background Impairment in a wide range of cognitive abilities has been consistently reported
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …
with many important life outcomes. We combine cognitive and genetic data from the …
Cognitive impairment associated with schizophrenia: from pathophysiology to treatment
DC Javitt - Annual Review of Pharmacology and Toxicology, 2023 - annualreviews.org
Cognitive impairment is a core feature of schizophrenia and a major contributor to poor
functional outcomes. Methods for assessment of cognitive dysfunction in schizophrenia are …
functional outcomes. Methods for assessment of cognitive dysfunction in schizophrenia are …
Cognitive impairment in psychotic illness: prevalence, profile of impairment, developmental course, and treatment considerations
Despite effective pharmacological treatments for psychotic symptoms (eg, hallucinations,
delusions), functional outcomes for people with psychotic disorders are often disappointing …
delusions), functional outcomes for people with psychotic disorders are often disappointing …
Antipsychotic drugs and cognitive function: a systematic review and pairwise network meta-analysis
L Feber, NL Peter, V Chiocchia… - Jama …, 2024 - jamanetwork.com
Importance Cognitive deficits are a substantial part of the symptoms of schizophrenia
spectrum disorders (SSDs) and contribute heavily to the burden of disease. Antipsychotic …
spectrum disorders (SSDs) and contribute heavily to the burden of disease. Antipsychotic …
Interplay among psychopathologic variables, personal resources, context-related factors, and real-life functioning in individuals with schizophrenia: a network analysis
Importance Enhanced understanding of factors associated with symptomatic and functional
recovery is instrumental to designing personalized treatment plans for people with …
recovery is instrumental to designing personalized treatment plans for people with …
The global cognitive impairment in schizophrenia: consistent over decades and around the world
Objective Schizophrenia results in cognitive impairments as well as positive, negative, and
disorganized symptomatology. The present study examines the extent to which these …
disorganized symptomatology. The present study examines the extent to which these …
The influence of illness‐related variables, personal resources and context‐related factors on real‐life functioning of people with schizophrenia
In people suffering from schizophrenia, major areas of everyday life are impaired, including
independent living, productive activities and social relationships. Enhanced understanding …
independent living, productive activities and social relationships. Enhanced understanding …
Factors associated with real-life functioning in persons with schizophrenia in a 4-year follow-up study of the Italian network for research on psychoses
Importance The goal of schizophrenia treatment has shifted from symptom reduction and
relapse prevention to functional recovery; however, recovery rates remain low. Prospective …
relapse prevention to functional recovery; however, recovery rates remain low. Prospective …