Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies

P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Immunomodulatory effect of adipose-derived stem cells: the cutting edge of clinical application

S Ceccarelli, P Pontecorvi, E Anastasiadou… - Frontiers in cell and …, 2020 - frontiersin.org
Adipose-derived stem cells (ASCs) represent a promising tool for soft tissue engineering as
well as for clinical treatment of inflammatory and autoimmune pathologies. The well …

Exosomes derived from human adipose mesenchymal stem cells attenuate hypertrophic scar fibrosis by miR-192-5p/IL-17RA/Smad axis

Y Li, J Zhang, J Shi, K Liu, X Wang, Y Jia, T He… - Stem Cell Research & …, 2021 - Springer
Background Hypertrophic scar (HS) is a fibro-proliferative disorder of dermis after burn or
trauma and usually leads to esthetic disfiguration and functionary impairment for patients …

Same or not the same? Comparison of adipose tissue-derived versus bone marrow-derived mesenchymal stem and stromal cells

M Strioga, S Viswanathan, A Darinskas… - Stem cells and …, 2012 - liebertpub.com
Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …

Concise review: adipose‐derived stem cells as a novel tool for future regenerative medicine

H Mizuno, M Tobita, AC Uysal - Stem cells, 2012 - academic.oup.com
The potential use of stem cell‐based therapies for the repair and regeneration of various
tissues and organs offers a paradigm shift that may provide alternative therapeutic solutions …

Role of adipose‐derived stem cells in wound healing

WU Hassan, U Greiser, W Wang - Wound repair and …, 2014 - Wiley Online Library
Impaired wound healing remains a challenge to date and causes debilitating effects with
tremendous suffering. Recent advances in tissue engineering approaches in the area of cell …

Adipose tissue-derived stem cells: immunomodulatory effects and therapeutic potential

S Al-Ghadban, BA Bunnell - Physiology, 2020 - journals.physiology.org
Adipose-derived stem cells (ASCs) can self-renew and differentiate along multiple cell
lineages. ASCs are also potently anti-inflammatory due to their inherent ability to regulate …

Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome

J Tang, D Shen, TG Caranasos, Z Wang… - Nature …, 2017 - nature.com
Stem cell therapy represents a promising strategy in regenerative medicine. However, cells
need to be carefully preserved and processed before usage. In addition, cell transplantation …

[HTML][HTML] Adipose tissue fibrosis: mechanisms, models, and importance

MK DeBari, RD Abbott - International journal of molecular sciences, 2020 - mdpi.com
Increases in adipocyte volume and tissue mass due to obesity can result in inflammation,
further dysregulation in adipose tissue function, and eventually adipose tissue fibrosis. Like …

[HTML][HTML] Fatty acid-treated induced pluripotent stem cell-derived human cardiomyocytes exhibit adult cardiomyocyte-like energy metabolism phenotypes

Y Horikoshi, Y Yan, M Terashvili, C Wells, H Horikoshi… - Cells, 2019 - mdpi.com
Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CMs)(iPSC-CMs) are
a promising cell source for myocardial regeneration, disease modeling and drug …