Synaptic mitochondria are crucial for maintaining synaptic activity due to their high energy
requirements, substantial calcium (Ca 2+) fluctuation, and neurotransmitter release at the …

An actin-spectrin lattice, the membrane periodic skeleton (MPS), protects axons from
breakage. MPS integrity relies on spectrin delivery via slow axonal transport, a process that …

Asymmetric transport of cargo across axonal branches is a field of active research.
Mechanisms contributing to preferential cargo transport along specific branches in vivo in …

Stationary clusters of vesicles are a prominent feature of axonal transport, but little is known
about their physiological and functional relevance to axonal transport. Here, we investigated …

Dynein is a microtubule‐dependent motor protein required for cell division, retrograde
intracellular transport, and intraflagellar transport (IFT). Dynein 1 and dynein 2 serve as …

Kinesins constitute a superfamily of microtubule (MT)-based motor proteins, which can
perform diverse biological functions in cells such as transporting vesicle, regulating MT …

Presynapses locally recycle synaptic vesicles to efficiently communicate information. During
use and recycling, proteins on the surface of synaptic vesicles break down and become less …

The molecular pathways that contribute to the onset of symptoms in tauopathy models,
including Alzheimer's disease (AD), are difficult to distinguish because multiple changes can …

Human cytomegalovirus (HCMV) is a common betaherpesvirus that infects between 40-90%
of adults worldwide. While infections are typically asymptomatic, spread from pregnant …

The physiological origin of the aperiodic signal present in the electrophysiological
recordings, called l/f neural noise, is unknown; nevertheless, it has been associated with …