Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions
The mitochondrial permeability transition (mPT) describes a Ca2+-dependent and
cyclophilin D (CypD)-facilitated increase of inner mitochondrial membrane permeability that …
cyclophilin D (CypD)-facilitated increase of inner mitochondrial membrane permeability that …
Hormonal orchestra: mastering mitochondria's role in health and disease
Mitochondria is a subcellular organelle involved in the pathogenesis of cellular stress,
immune responses, differentiation, metabolic disorders, aging, and death by regulating …
immune responses, differentiation, metabolic disorders, aging, and death by regulating …
Inorganic polyphosphate and ion transport across biological membranes
Inorganic polyphosphate (polyP) is widely recognized for playing important roles and
processes involved in energy and phosphate storage, regulation of gene expression, and …
processes involved in energy and phosphate storage, regulation of gene expression, and …
Protein folding and unfolding: proline cis‐trans isomerization at the c subunits of F1FO‐ATPase might open a high conductance ion channel
S Nesci - Proteins: Structure, Function, and Bioinformatics, 2022 - Wiley Online Library
The c subunits, which constitute the c‐ring apparatus of the F1FO‐ATPase, could be the
main components of the mitochondrial permeability transition pore (mPTP). The well‐known …
main components of the mitochondrial permeability transition pore (mPTP). The well‐known …
Cyclophilin D in Mitochondrial Dysfunction: A Key Player in Neurodegeneration?
G Coluccino, VP Muraca, A Corazza, G Lippe - Biomolecules, 2023 - mdpi.com
Mitochondrial dysfunction plays a pivotal role in numerous complex diseases.
Understanding the molecular mechanisms by which the “powerhouse of the cell” turns into …
Understanding the molecular mechanisms by which the “powerhouse of the cell” turns into …
[HTML][HTML] A hypothetical mechanism capable to reflect the features of the mitochondrial permeability transition pore channel
AG Dimitrov - Advances in Redox Research, 2024 - Elsevier
Mitochondrial permeability transition pore (mPTP) channel plays a central role in cell death
because it mediates the effect of a sudden large opening of the inner mitochondrial …
because it mediates the effect of a sudden large opening of the inner mitochondrial …
[HTML][HTML] Similarities between fibroblasts and cardiomyocytes in the study of the permeability transition pore
The investigation of biological processes involved in cardiovascular diseases and the study
of new cardioprotective strategies and therapeutic targets in human specimens are …
of new cardioprotective strategies and therapeutic targets in human specimens are …
[ZITATION][C] The Contribution of Mitochondrial Calcium Flux to Permeability Transition Pore Opening
F Ullah - 2022 - Quaid i Azam University, Islamabad