Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …

Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

Global climate change linked to the accumulation of greenhouse gases has caused
concerns regarding the use of fossil fuels as the major energy source. To mitigate climate …

New synthetic biology capabilities hold the promise of dramatically improving our ability to
engineer biological systems. However, a fundamental hurdle in realizing this potential is our …

Microorganisms directly and indirectly contribute to production of diverse biofuels.
Heterotrophic microorganisms are being used for commercial production of biofuels such as …

The more than 50,000 isoprenoids found in nature are all derived from the 5-carbon
diphosphates isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) …

Ongoing progress in synthetic biology, metabolic engineering, and catalysis continues to
produce a diverse array of advanced biofuels with complex molecular structure and …

The development of sustainable energy solutions that reduce global carbon emissions,
while maintaining high living standards, is one of the grand challenges of the current …

The future bioeconomy promises drop-in or performance-advantaged biofuels and
bioproducts derived from lignocellulosic biomass, substantial greenhouse gas emissions …

Cell-free metabolic engineering (CFME) is advancing a powerful paradigm for accelerating
the design and synthesis of biosynthetic pathways. However, as most cell-free biomolecule …