The human antibody response to dengue virus infection
WMPB Wahala, AM De Silva - Viruses, 2011 - mdpi.com
Dengue viruses (DENV) are the causative agents of dengue fever (DF) and dengue
hemorrhagic fever (DHF). Here we review the current state of knowledge about the human …
hemorrhagic fever (DHF). Here we review the current state of knowledge about the human …
Vaccine development as a means to control dengue virus pathogenesis: do we know enough?
TC Pierson, MS Diamond - Annual Review of Virology, 2014 - annualreviews.org
Dengue virus (DENV) is a mosquito-transmitted RNA virus responsible for 390 million
infections each year and significant morbidity and mortality throughout tropical and …
infections each year and significant morbidity and mortality throughout tropical and …
Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions
R De Alwis, SA Smith, NP Olivarez… - Proceedings of the …, 2012 - National Acad Sciences
Dengue is a mosquito-borne flavivirus that is spreading at an unprecedented rate and has
developed into a major health and economic burden in over 50 countries. Even though …
developed into a major health and economic burden in over 50 countries. Even though …
A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins
Abstract Dengue virus (DENV) infects~ 400 million people annually. There is no licensed
vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a …
vaccine or therapeutic drug. Only a small fraction of the total DENV-specific antibodies in a …
A potent anti‐dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface
G Fibriansah, JL Tan, SA Smith… - EMBO molecular …, 2014 - embopress.org
Dengue virus (DENV), which consists of four serotypes (DENV 1‐4), infects over 400 million
people annually. Previous studies have indicated most human monoclonal antibodies (HMA …
people annually. Previous studies have indicated most human monoclonal antibodies (HMA …
Progress towards a dengue vaccine
DP Webster, J Farrar… - The Lancet infectious …, 2009 - thelancet.com
The spread of dengue virus throughout the tropics represents a major, rapidly growing
public health problem with an estimated 2· 5 billion people at risk of dengue fever and the …
public health problem with an estimated 2· 5 billion people at risk of dengue fever and the …
A single dose of any of four different live attenuated tetravalent dengue vaccines is safe and immunogenic in flavivirus-naive adults: a randomized, double-blind …
AP Durbin, BD Kirkpatrick, KK Pierce… - The Journal of …, 2013 - academic.oup.com
Background. Dengue virus (DENV) causes hundreds of millions of infections annually. Four
dengue serotypes exist, and previous infection with one serotype increases the likelihood of …
dengue serotypes exist, and previous infection with one serotype increases the likelihood of …
Dengue virus neutralizing antibody: a review of targets, cross-reactivity, and antibody-dependent enhancement
Dengue is the most common viral infection spread by mosquitoes, prevalent in tropical
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …
countries. The acute dengue virus (DENV) infection is a benign and primarily febrile illness …
Ligation of Fc gamma receptor IIB inhibits antibody-dependent enhancement of dengue virus infection
KR Chan, SLX Zhang, HC Tan… - Proceedings of the …, 2011 - National Acad Sciences
The interaction of antibodies, dengue virus (DENV), and monocytes can result in either
immunity or enhanced virus infection. These opposing outcomes of dengue antibodies have …
immunity or enhanced virus infection. These opposing outcomes of dengue antibodies have …
[HTML][HTML] Human genetic determinants of dengue virus susceptibility
LL Coffey, E Mertens, AC Brehin… - Microbes and …, 2009 - Elsevier
Dengue virus (DENV) is an emerging mosquito-borne pathogen that produces significant
morbidity worldwide resulting in an estimated 50–100 million infections annually. DENV …
morbidity worldwide resulting in an estimated 50–100 million infections annually. DENV …