Skeletal muscle: A review of molecular structure and function, in health and disease
Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …
the structural and functional complexity of this important anatomical tissue, designed to …
The role of single-protein elasticity in mechanobiology
In addition to biochemical signals and genetic considerations, mechanical forces are rapidly
emerging as a master regulator of human physiology. However, the molecular mechanisms …
emerging as a master regulator of human physiology. However, the molecular mechanisms …
Structure of the native myosin filament in the relaxed cardiac sarcomere
The thick filament is a key component of sarcomeres, the basic units of striated muscle.
Alterations in thick filament proteins are associated with familial hypertrophic …
Alterations in thick filament proteins are associated with familial hypertrophic …
[HTML][HTML] The M-band: The underestimated part of the sarcomere
The sarcomere is the basic unit of the myofibrils, which mediate skeletal and cardiac Muscle
contraction. Two transverse structures, the Z-disc and the M-band, anchor the thin (actin and …
contraction. Two transverse structures, the Z-disc and the M-band, anchor the thin (actin and …
Steering chemical reactions with force
Chemical reactivity underlies our fundamental understanding of many physical and
biological phenomena. Chemical reactions are typically initiated by heat, electric current or …
biological phenomena. Chemical reactions are typically initiated by heat, electric current or …
Dynamic changes in the mouse skeletal muscle proteome during denervation-induced atrophy
F Lang, S Aravamudhan, H Nolte… - Disease models & …, 2017 - journals.biologists.com
Loss of neuronal stimulation enhances protein breakdown and reduces protein synthesis,
causing rapid loss of muscle mass. To elucidate the pathophysiological adaptations that …
causing rapid loss of muscle mass. To elucidate the pathophysiological adaptations that …
Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179
Precise synapse formation is essential for normal functioning of the nervous system. Retinal
photoreceptors establish selective contacts with bipolar cells, aligning the neurotransmitter …
photoreceptors establish selective contacts with bipolar cells, aligning the neurotransmitter …
In situ structures from relaxed cardiac myofibrils reveal the organization of the muscle thick filament
The thick filament is a key component of sarcomeres, the basic force-generating and load-
bearing unit of striated muscle. Mutations in thick filament proteins are associated with …
bearing unit of striated muscle. Mutations in thick filament proteins are associated with …
The insect perspective on Z-disc structure and biology
Myofibrils are the intracellular structures formed by actin and myosin filaments. They are
paracrystalline contractile cables with unusually well-defined dimensions. The sliding of …
paracrystalline contractile cables with unusually well-defined dimensions. The sliding of …
Phosphoproteomic insight into the changes in structural proteins of muscle architecture associated with texture softening of grass carp (Ctenopharyngodon idella) …
L Ge, N Wang, X Li, Y Huang, K Li, Y Zuo - Food Chemistry, 2023 - Elsevier
Texture is an important sensory attribute of fish affected by modifications of structural
proteins in muscle architecture. To investigate the changes in protein phosphorylation …
proteins in muscle architecture. To investigate the changes in protein phosphorylation …