Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …

Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …

Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and
tissue development. The molecular mechanisms determining how and where filopodia grow …

The actin cytoskeleton plays a crucial role in many cellular processes while its
reorganization is important in maintaining cell homeostasis. However, in the case of cancer …

The tightly coordinated, spatiotemporal control of actin filament remodeling provides the
basis of fundamental cellular processes, such as cell migration and adhesion. Specific …

ADP-ribose (ADPr) readers are essential components of ADP-ribosylation signaling, which
regulates genome maintenance and immunity. The identification and discrimination …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by
more than sixty genes identified through classic linkage analysis and new sequencing …

Tunnelling nanotubes (TNTs) connect distant cells and mediate cargo transfer for
intercellular communication in physiological and pathological contexts. How cells generate …

Trichomonas vaginalis, the etiologic agent of the most common non-viral sexually
transmitted infection worldwide. With an estimated annual prevalence of 276 million new …

Profilin is a ubiquitously expressed protein well known as a key regulator of actin
polymerisation. The actin cytoskeleton is involved in almost all cellular processes including …