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Design of hydrogel-based scaffolds for the treatment of spinal cord injuries
N Ghane, MH Beigi, S Labbaf… - Journal of Materials …, 2020 - pubs.rsc.org
Spinal cord injury (SCI) is a traumatic lesion that diminishes sensory and/or motor neuronal
functionality, directly affecting the quality of the patient's life. Due to the central nervous …
functionality, directly affecting the quality of the patient's life. Due to the central nervous …
Experimental spinal cord injury and behavioral tests in laboratory rats
Traumatic spinal cord injury (SCI) results in some serious neurophysiological consequences
that alter healthy body functions and devastate the quality of living of individuals. To find a …
that alter healthy body functions and devastate the quality of living of individuals. To find a …
Photobiomodulation inhibits the activation of neurotoxic microglia and astrocytes by inhibiting Lcn2/JAK2-STAT3 crosstalk after spinal cord injury in male rats
X Wang, X Li, X Zuo, Z Liang, T Ding, K Li, Y Ma… - Journal of …, 2021 - Springer
Background Neurotoxic microglia and astrocytes begin to activate and participate in
pathological processes after spinal cord injury (SCI), subsequently causing severe …
pathological processes after spinal cord injury (SCI), subsequently causing severe …
Engineered Macrophage Membrane‐Coated Nanoparticles with Enhanced CCR2 Expression Promote Spinal Cord Injury Repair by Suppressing Neuroinflammation …
C Gu, X Geng, Y Wu, Y Dai, J Zeng, Z Wang, H Fang… - Small, 2024 - Wiley Online Library
Spinal cord injury (SCI) is a severe neurological disorder characterized by significant
disability and limited treatment options. Mitigating the secondary inflammatory response …
disability and limited treatment options. Mitigating the secondary inflammatory response …
Cannabinoid receptor-2 attenuates neuroinflammation by promoting autophagy-mediated degradation of the NLRP3 inflammasome post spinal cord injury
F Jiang, M **a, Y Zhang, J Chang, J Cao… - Frontiers in …, 2022 - frontiersin.org
Background Neuroinflammation following spinal cord injury (SCI) results in prolonged
neurological damage and locomotor dysfunction. Polarization of microglia is vital to …
neurological damage and locomotor dysfunction. Polarization of microglia is vital to …
Growth differentiation factor 15 regulates oxidative stress-dependent ferroptosis post spinal cord injury by stabilizing the p62-Keap1-Nrf2 signaling pathway
M **a, Q Zhang, Y Zhang, R Li, T Zhao… - Frontiers in Aging …, 2022 - frontiersin.org
Background Spinal cord injury (SCI) is a severe traumatic disorder of the central nervous
system (CNS) that causes irreversible damage to the nervous tissue. The consequent …
system (CNS) that causes irreversible damage to the nervous tissue. The consequent …
[HTML][HTML] Alpha-tocopherol inhibits ferroptosis and promotes neural function recovery in rats with spinal cord injury via downregulating Alox15
R Zhu, Y Kang, Q Li, K Peng, X Shi, Z Yin… - Biomedicine & …, 2024 - Elsevier
Spinal cord injury (SCI) is a type of central nervous system (CNS) injury in which ferroptosis
is becoming a promising target for treatment. Alpha-tocopherol (Vitamin E, Vit E) is a …
is becoming a promising target for treatment. Alpha-tocopherol (Vitamin E, Vit E) is a …
Long-Acting Heterodimeric Paclitaxel–Idebenone Prodrug-Based Nanomedicine Promotes Functional Recovery after Spinal Cord Injury
Z Xu, X Liu, Y Pang, Z Chen, Y Jiang, T Liu, J Zhang… - Nano Letters, 2024 - ACS Publications
After spinal cord injury (SCI), successive systemic administration of microtubule-stabilizing
agents has been shown to promote axon regeneration. However, this approach is limited by …
agents has been shown to promote axon regeneration. However, this approach is limited by …
[HTML][HTML] Targeted transplantation of engineered mitochondrial compound promotes functional recovery after spinal cord injury by enhancing macrophage …
J Xu, C Shi, F Yuan, Y Ding, Y **e, Y Liu, F Zhu, H Lu… - Bioactive Materials, 2024 - Elsevier
Mitochondria are crucial in sustaining and orchestrating cellular functions. Capitalizing on
this, we explored mitochondrial transplantation as an innovative therapeutic strategy for …
this, we explored mitochondrial transplantation as an innovative therapeutic strategy for …
Multifunctional hierarchical nanoplatform with anisotropic bimodal mesopores for effective neural circuit reconstruction after spinal cord injury
F Kong, H Yu, L Gao, E **ng, Y Yu, X Sun, W Wang… - ACS …, 2024 - ACS Publications
A persistent inflammatory response, intrinsic limitations in axonal regenerative capacity, and
widespread presence of extrinsic axonal inhibitors impede the restoration of motor function …
widespread presence of extrinsic axonal inhibitors impede the restoration of motor function …