Highlights•Climate is changing fastest at high latitudes and in winter.•Phenological shifts in
response to climate change are common.•Warmer winters may influence spring phenology …

Highlights•Untargeted screening, without effective metabolite identification, limits
insight.•Well-curated metabolite databases are essential.•Time-series and tissue-specific …

Organisms inhabiting highly seasonal environments must cope with a wide range of
environmentally induced challenges. Many seasonal challenges require extensive …

Many organisms enter a dormant state in their life cycle to deal with predictable changes in
environments over the course of a year. The timing of dormancy is therefore a key seasonal …

Diapause is an alternative life-history strategy that allows organisms to enter developmental
arrest in anticipation of unfavorable conditions. Diapause is widespread among insects and …

Simple Summary Diapause is a programmed developmental arrest coupled with an evident
reduction in metabolic rate and a dramatic increase in stress tolerance. Sitodiplosis …

Most previous studies on gene expression during insect diapause do not address among-
tissue variation in physiological processes. We measured transcriptomic changes during …

The life cycles of animals vary in relation to local climate, as a result of both direct
environmental effects and population‐level variation in plastic responses. Insects often …

The monarch butterfly (Danaus plexippus) complements its iconic migration with diapause, a
hormonally controlled developmental programme that contributes to winter survival at …

Low temperatures associated with winter can limit the survival of organisms, especially
ectotherms whose body temperature is similar to their environment. However, there is a gap …