Research progress on the source, production, and anti-cancer mechanisms of paclitaxel

Y Yan-Hua, MAO Jia-Wang, TAN **ao-Li - Chinese journal of natural …, 2020 - Elsevier
Paclitaxel, a tetracyclic diterpenoid compounds, was firstly isolated from the bark of the
Pacific yew trees. Currently, as a low toxicity, high efficiency, and broad-spectrum natural …

Endophytic fungi: novel sources of anticancer lead molecules

S Chandra - Applied microbiology and biotechnology, 2012 - Springer
Cancer is a major killer disease all over the world and more than six million new cases are
reported every year. Nature is an attractive source of new therapeutic compounds, as a …

Microbial endophytes: emerging trends and biotechnological applications

S Agrawal, A Bhatt - Current Microbiology, 2023 - Springer
A plethora of knowledge on the role of endophytic microorganisms has been reported in
recent years. The cooperative chemistry between the endophytes and the internal host …

Characterization of aflatoxin producing Aspergillus flavus from food and feed samples

MD Fakruddin, A Chowdhury, MN Hossain, MM Ahmed - SpringerPlus, 2015 - Springer
Aspergillus flavus is one of the major producers of aflatoxin and can contaminate wide range
of agricultural commodities either in field or in storage. 15 presumptive Aspergillus flavus …

Biologically significant and recently isolated alkaloids from endophytic fungi

S Daley, GA Cordell - Journal of Natural Products, 2021 - ACS Publications
Biologically Significant and Recently Isolated Alkaloids from Endophytic Fungi | Journal of
Natural Products Recently Viewedclose modal Pair your accounts. Export articles to Mendeley …

Metabolites from Clonostachys Fungi and Their Biological Activities

P Han, X Zhang, D Xu, B Zhang, D Lai, L Zhou - Journal of fungi, 2020 - mdpi.com
Clonostachys (teleomorph: Bionectria) fungi are well known to produce a variety of
secondary metabolites with various biological activities to show their pharmaceutical and …

Production of paclitaxel with anticancer activity by two local fungal endophytes, Aspergillus fumigatus and Alternaria tenuissima

AA Ismaiel, AS Ahmed, IA Hassan… - Applied microbiology …, 2017 - Springer
Among 60 fungal endophytes isolated from twigs, bark, and mature leaves of different plant
species, two fungal isolates named TXD105 and TER995 were capable of producing …

Protective and therapeutic effects of lactic acid bacteria against aflatoxin B1 toxicity to rat organs

H Ashi, MHK Almalki, EA Hamed, WS Ramadan… - Microorganisms, 2023 - mdpi.com
Background: Aflatoxin (AF), a metabolite of Aspergillus flavus, is injurious to vital body
organs. The bacterial defense against such mycotoxins has attracted significant attention …

[HTML][HTML] Elicitors stimulate paclitaxel production by endophytic fungi isolated from ecologically altered Taxus baccata

HA El-Bialy, HS El-Bastawisy - Journal of Radiation Research and Applied …, 2020 - Elsevier
The commercial production of paclitaxel; the most potent anti-cancer drug, is based on its
extraction from Taxus spp (yews) or microbial fermentation from yews' endophytes. The …

Fungal endophytes of Taxus species and regulatory effect of two strains on taxol synthesis

H Zhang, W Lin, R Ma, Y Zang, K Hou, Z Xu, X **… - BMC microbiology, 2024 - Springer
Abstract Background Taxol, derived from Taxus trees, is a valuable natural resource for the
development of anticancer drugs. Endophytic fungi from Taxus trees are a promising …