The γδ T cell lineage in humans remains much of an enigma due to the low number of
defined antigens, the non-canonical ways in which these cells respond to their environment …

γδ T cells are the unique T cell subgroup with their T cell receptors composed of γ chain and
δ chain. Unlike αβ T cells, γδ T cells are non-MHC-restricted in recognizing tumor antigens …

In humans, Vγ9Vδ2 T cells detect tumor cells and microbial infections, including
Mycobacterium tuberculosis, through recognition of small pyrophosphate containing organic …

The study of T cell memory and the target of vaccine design have focused on memory
subsumed by T cells bearing the αβ T cell receptor. Alternatively, γδ T cells are thought to …

Starting at birth, the immune system of newborns and children encounters and is influenced
by environmental challenges. It is still not completely understood how γδ T cells emerge and …

Abstract Bacillus Calmette–Guérin vaccine is well known for inducing trained immunity in
myeloid and natural killer cells, which can explain its cross-protective effect against …

Human γδ T cells expressing the Vγ2Vδ2 TCR play important roles in immune responses to
microbial pathogens by monitoring prenyl pyrophosphate isoprenoid metabolites. Most adult …

Most human γδ T cells express Vγ2Vδ2 TCRs and play important roles in microbial and
tumor immunity. Vγ2Vδ2 T cells are stimulated by self-and foreign prenyl pyrophosphate …

Epstein-Barr virus-induced lymphoproliferative disease (EBV-LPD) after transplantation
remains a serious and life-threatening complication. Herein we showed that the …

Background Influenza virus is a cause of substantial annual morbidity and mortality
worldwide. The potential emergence of a new pandemic strain (eg, avian influenza virus) is …