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The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome
Fetal growth restriction (FGR) is a significant complication of pregnancy describing a fetus
that does not grow to full potential due to pathological compromise. FGR affects 3–9% of …
that does not grow to full potential due to pathological compromise. FGR affects 3–9% of …
Network models to enhance the translational impact of cross-species studies
Neuroscience studies are often carried out in animal models for the purpose of
understanding specific aspects of the human condition. However, the translation of findings …
understanding specific aspects of the human condition. However, the translation of findings …
[HTML][HTML] Prenatal exposure to air pollution is associated with structural changes in the neonatal brain
Background Prenatal exposure to air pollution is associated with adverse neurologic
consequences in childhood. However, the relationship between in utero exposure to air …
consequences in childhood. However, the relationship between in utero exposure to air …
Early brain connectivity alterations and cognitive impairment in a rat model of Alzheimer's disease
Abstract Background Animal models of Alzheimer's disease (AD) are essential to
understanding the disease progression and to development of early biomarkers. Because …
understanding the disease progression and to development of early biomarkers. Because …
Models of Intrauterine growth restriction and fetal programming in rabbits
Intrauterine growth restriction (IUGR) affects approximately 10% of human pregnancies
globally and has immediate and life‐long consequences for offspring health. However, the …
globally and has immediate and life‐long consequences for offspring health. However, the …
Detection and assessment of brain injury in the growth-restricted fetus and neonate
Fetal growth restriction (FGR) is a common complication of pregnancy and, in severe cases,
is associated with elevated rates of perinatal mortality, neonatal morbidity, and poor …
is associated with elevated rates of perinatal mortality, neonatal morbidity, and poor …
M2 cortex-dorsolateral striatum stimulation reverses motor symptoms and synaptic deficits in Huntington's disease
S Fernández-García, S Conde-Berriozabal… - Elife, 2020 - elifesciences.org
Huntington's disease (HD) is a neurological disorder characterized by motor disturbances.
HD pathology is most prominent in the striatum, the central hub of the basal ganglia. The …
HD pathology is most prominent in the striatum, the central hub of the basal ganglia. The …
Thyroid hormone analogues: Promising therapeutic avenues to improve the neurodevelopmental outcomes of intrauterine growth restriction
G Chincarini, DW Walker, F Wong… - Journal of …, 2024 - Wiley Online Library
Intrauterine growth restriction (IUGR) is a pregnancy complication impairing fetal growth and
development. The compromised development is often attributed to disruptions of oxygen …
development. The compromised development is often attributed to disruptions of oxygen …
Montelukast reduces grey matter abnormalities and functional deficits in a mouse model of inflammation-induced encephalopathy of prematurity
AG Yates, E Kislitsyna, C Alfonso Martin… - Journal of …, 2022 - Springer
Encephalopathy of prematurity (EoP) affects approximately 30% of infants born< 32 weeks
gestation and is highly associated with inflammation in the foetus. Here we evaluated the …
gestation and is highly associated with inflammation in the foetus. Here we evaluated the …
Programming the brain: Common outcomes and gaps in knowledge from animal studies of IUGR
IUGR in humans is associated with impaired pre-and postnatal neurodevelopment, and
subsequent postnatal cognition, resulting in lower IQ, poorer memory, visuomotor and …
subsequent postnatal cognition, resulting in lower IQ, poorer memory, visuomotor and …