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Mass spectrometry-based techniques to elucidate the sugar code
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …
and glycans. Although glycans are essential to all living organisms, surprisingly little is …
Gas-phase infrared spectroscopy of glycans and glycoconjugates
K Greis, C Kirschbaum, G von Helden… - Current Opinion in …, 2022 - Elsevier
Glycans are intrinsically complex biomolecules that pose particular analytical challenges.
Standard workflows for glycan analysis are based on mass spectrometry, often coupled with …
Standard workflows for glycan analysis are based on mass spectrometry, often coupled with …
Toward high-throughput cryogenic IR fingerprinting of mobility-separated glycan isomers
Infrared (IR) spectroscopy is a powerful tool used to infer detailed structural information on
molecules, often in conjunction with quantum-chemical calculations. When applied to …
molecules, often in conjunction with quantum-chemical calculations. When applied to …
Predicting structural motifs of glycosaminoglycans using cryogenic infrared spectroscopy and random forest
J Riedel, M Lettow, M Grabarics… - Journal of the …, 2023 - ACS Publications
In recent years, glycosaminoglycans (GAGs) have emerged into the focus of biochemical
and biomedical research due to their importance in a variety of physiological processes …
and biomedical research due to their importance in a variety of physiological processes …
High-throughput multiplexed infrared spectroscopy of ion mobility-separated species using Hadamard transform
V Yatsyna, AH Abikhodr, A Ben Faleh… - Analytical …, 2022 - ACS Publications
Coupling vibrational ion spectroscopy with high-resolution ion mobility separation offers a
promising approach for detailed analysis of biomolecules in the gas phase. Improvements in …
promising approach for detailed analysis of biomolecules in the gas phase. Improvements in …
Introducing ion mobility mass spectrometry in brain glycosaminoglycomics: application to chondroitin/dermatan sulfate octasaccharide domains
M Sarbu, DG Seidler, DE Clemmer… - Journal of the American …, 2024 - ACS Publications
Glycosaminoglycans (GAGs) are sulfated linear O-glycan chains abundantly expressed in
the extracellular matrix (ECM). Among GAGs, chondroitin sulfate (CS) and dermatan sulfate …
the extracellular matrix (ECM). Among GAGs, chondroitin sulfate (CS) and dermatan sulfate …
Glycomics by ion mobility tandem mass spectrometry of chondroitin sulfate disaccharide domain in biglycan
M Sarbu, R Ica, E Sharon, DE Clemmer… - Journal of Mass …, 2023 - Wiley Online Library
Biglycan (BGN), a small leucine‐rich repeat proteoglycan, is involved in a variety of
pathological processes including malignant transformation, for which the upregulation of …
pathological processes including malignant transformation, for which the upregulation of …
Cold-ion Spectroscopy of Carbohydrates
K PAGEL - Glycoprotein Analysis, 2024 - books.google.com
Carbohydrates are ubiquitous in nature. 1, 2 Besides their function as energy storage,
glycans and glycoconjugates involving peptides (glycopeptides), proteins (glycoproteins) …
glycans and glycoconjugates involving peptides (glycopeptides), proteins (glycoproteins) …
Cold-ion Spectroscopy of Carbohydrates
Carbohydrates are ubiquitous in nature. 1, 2 Besides their function as energy storage,
glycans and glycoconjugates involving peptides (glycopeptides), proteins (glycoproteins) …
glycans and glycoconjugates involving peptides (glycopeptides), proteins (glycoproteins) …
Methods and Materials for Studying Proteoglycans and Glycosaminoglycans
Cellular processes in multi-cellular organisms depend on the interaction of biological
molecules, which is driven by specific molecular recognition. Glycoproteins present on the …
molecules, which is driven by specific molecular recognition. Glycoproteins present on the …