OBJECTIVES: Histidine-tryptophan-ketoglutarate (HTK–Custodiol) cardioplegic solution is
administered as one single dose for more than 2 hours of ischemia. No prospective …

While cardioplegia has been used on millions of patients during the last decades, the
debate over the best technique is still going on. Cardioplegia is not only meant to provide a …

Objective Single-dose antegrade crystalloid cardioplegia with Custodiol-HTK (histidine-
tryptophan-ketoglutarate) has been used for many years. Its safety and efficacy were …

Objectives. To clarify the reliability of the one-shot histidine–tryptophane–ketoglutarate
(HTK) cardioplegia for right ventricular (RV) myocardial protection during mitral surgery, in …

BACKGROUND: A single-dose strategy for cardioplegia is desired in minimal invasive
approaches to valve surgery and aortic arch repairs. We hypothesized that a single infusion …

One stage repair of interrupted aortic arch (IAA) associated with cardiac anomalies in
neonates and infants is challenging for the entire surgical team. Deep hypothermic …

Objective Our unit began a minimally invasive mitral surgery (MIMS) program utilising
antegrade Custodiol solution as the sole cardioplegia. The aim of this paper is to report our …

OBJECTIVES Minimally invasive aortic valve replacement (MIAVR) can be technically
demanding and may lead to prolonged operative time. We evaluated the intraoperative and …

Objective Minimally invasive mitral valve surgery may require a prolonged period of
myocardial ischemia. Cardioplegic solutions that necessitate a single dose for adequate …

Methods: A retrospective cohort study of patients who underwent CABG with surgical patch
angioplasty of the coronary artery (reconstruction group) or standard CABG alone (standard …