BACKGROUND The human brain contains about 100 billion neurons, each of which makes
thousands of synaptic connections. Although individual neurons can themselves be …

Tremendous progress has been made since Neuron published our Primer on genetic
dissection of neural circuits 10 years ago. Since then, cell-type-specific anatomical …

The body–brain axis is emerging as a principal conductor of organismal physiology. It
senses and controls organ function,, metabolism and nutritional state,–. Here we show that a …

Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …

Brain organoids created from human pluripotent stem cells represent a promising approach
for brain repair. They acquire many structural features of the brain and raise the possibility of …

Ventral midbrain dopaminergic neurons project to the striatum as well as the cortex and are
involved in movement control and reward-related cognition. In Parkinson's disease …

INTRODUCTION Glial cells of the central nervous system (CNS), including astrocytes and
microglia, play critical roles in development, tissue repair, and homeostasis. However …

INTRODUCTION In 1853, Sydney Whiting wrote in his classic Memoirs of a Stomach,“… and
between myself and that individual Mr. Brain, there was established a double set of electrical …

Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …

The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown
how the two structures organize into functional networks to mediate specific behaviors. Here …