The intricacy of diseases, shaped by intrinsic processes like immune system exhaustion and
hyperactivation, highlights the potential of immune renormalization as a promising strategy …

Ferroptosis is a pervasive non-apoptotic form of cell death highly relevant in various
degenerative diseases and malignancies. The hallmark of ferroptosis is uncontrolled and …

The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Background Myeloproliferative neoplasms, such as polycythemia vera, essential
thrombocythemia, and myelofibrosis, are chronic hematologic cancers with varied …

Artificial intelligence (AI) is a rapidly evolving field of computer science that involves the
development of computational programs that can mimic human intelligence. In particular …

Abstract Background Hematologic malignancies (HMs) are a heterogeneous group of
cancers that comprise diverse subgroups of neoplasms. So far, despite the major …

Cytogenetics has long represented a critical component in the clinical evaluation of
hematologic malignancies. Chromosome banding studies provide a simultaneous snapshot …

Piwi-interacting RNAs (piRNAs) are a class of short chain noncoding RNAs that are
constituted by 26-30 nucleotides (nt) and can couple with PIWI protein family. piRNAs were …

In clinical diagnosis, the capability of exosomes to serve as biomarkers is one of the most
important biological functions of exosomes. The superior stability of exosome biomarkers …

Hematopoietic stem cells (HSCs) possess two important properties such as self-renewal and
differentiation. These properties of HSCs are maintained through hematopoiesis. This …