In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

Balanced immune responses in the eyes are crucial to preserve vision. The ocular immune
system has long been considered distinct, owing to the so-called 'immune privilege'of its …

The ocular surface, which forms the interface between the eye and the external environment,
includes the cornea, corneoscleral limbus, the conjunctiva and the accessory glands that …

Stroke is the second leading cause of death worldwide and has two major subtypes:
ischemic stroke and hemorrhagic stroke. Neuroinflammation is a pathological hallmark of …

The corneal epithelium contains a population of resident immune cells commonly referred to
as dendritic cells (DCs), or Langerhans cells. A unique advantage of the transparent cornea …

Decorin is an archetypal member of the small leucine-rich proteoglycan gene family and is
involved in various biological functions and many signaling networks, interacting with extra …

Background: Induced pluripotent stem cells-derived exosomes (iPSCs-Exo) can effectively
treat spinal cord injury (SCI) in mice. But the role of iPSCs-Exo in SCI mice and its molecular …

Adipose-derived stem cells (ADSCs) are employed as a promising alternative in treating
cartilage injury. Regulating the inflammatory “fingerprint” of ADSCs to improve their anti …

The ocular surface microbiota plays a critical role in maintaining corneal homeostasis, but its
disruption and subsequent effects on corneal functions remain poorly understood. This study …

Background Corneal immune cells interact with corneal sensory nerves during both
homeostasis and inflammation. This study sought to evaluate temporal changes to corneal …