Engaging isatins in multicomponent reactions (MCRs)–easy access to structural diversity

P Brandão, CS Marques, EP Carreiro… - The Chemical …, 2021 - Wiley Online Library
Multicomponent reactions (MCRs) are a valuable tool in diversity‐oriented synthesis. Its
application to privileged structures is gaining relevance in the fields of organic and …

Decade Advance of Isatin in Three‐component Reactions

S Zhang, D Huang, J Wu, Z Wang - Asian Journal of Organic …, 2023 - Wiley Online Library
Isatin is an important building block in organic synthesis. The electron‐deficient carbonyl in
C‐3 site is similar to aldehyde. C‐3 carbonyl is also able to function as the O‐nucleophile …

Magnetically recoverable silica catalysed solvent-free domino Knoevenagel-hetero-Diels–Alder reaction to access divergent chromenones

M Suri, FL Hussain, C Gogoi, P Das… - Organic & Biomolecular …, 2020 - pubs.rsc.org
A three-component domino Knoevenagel-hetero-Diels–Alder (DKHDA) reaction between 1,
3-dicarbonyl, aldehydes/ketones, and alkenes/alkynes leading to the divergent synthesis of …

Ammonium Chloride Assisted Microwave Mediated Domino Multicomponent Reaction: An Efficient and Sustainable Synthesis of Quinazolin‐4(3H)‐imines under …

AS Hussen, S Bagchi, A Sharma - ChemistrySelect, 2019 - Wiley Online Library
A novel multicomponent synthesis of quinazolin‐4 (3H)‐imines starting from simple and
readily available inputs is described. Herein, we report efficient and environmentally benign …