Lab-on-chip technology for chronic disease diagnosis

J Wu, M Dong, C Rigatto, Y Liu, F Lin - NPJ digital medicine, 2018‏ - nature.com
Various types of chronic diseases (CD) are the leading causes of disability and death
worldwide. While those diseases are chronic in nature, accurate and timely clinical decision …

Advances in biosensor technologies for acute kidney injury

E Derin, F Inci - ACS sensors, 2021‏ - ACS Publications
Acute kidney injury (AKI) is one of the most prevalent and complex clinical syndromes with
high morbidity and mortality. The traditional diagnosis parameters are insufficient regarding …

96-well microtiter plate made of paper: a printed chemosensor array for quantitative detection of saccharides

X Lyu, V Hamedpour, Y Sasaki, Z Zhang… - Analytical …, 2020‏ - ACS Publications
Simple, rapid, and accurate detection methods for saccharides are potentially applicable to
various fields such as clinical and food chemistry. However, the practical applications of on …

Digital biology and chemistry

D Witters, B Sun, S Begolo, J Rodriguez-Manzano… - Lab on a Chip, 2014‏ - pubs.rsc.org
This account examines developments in “digital” biology and chemistry within the context of
microfluidics, from a personal perspective. Using microfluidics as a frame of reference, we …

A prototype point-of-use assay for measuring heavy metal contamination in water using time as a quantitative readout

GG Lewis, JS Robbins, ST Phillips - Chemical Communications, 2014‏ - pubs.rsc.org
This Communication describes a prototype quantitative paper-based assay that
simultaneously measures the levels of Pb2+ and Hg2+ in water. The assay requires only …

A cationic surfactant-decorated liquid crystal sensing platform for simple and sensitive detection of acetylcholinesterase and its inhibitor

Y Wang, Q Hu, Y Guo, L Yu - Biosensors and Bioelectronics, 2015‏ - Elsevier
In this paper, construction of the liquid crystal (LC)-based sensing platform for simple and
sensitive detection of acetylcholinesterase (AChE) and its inhibitor using a cationic …

A microfluidic platform with digital readout and ultra-low detection limit for quantitative point-of-care diagnostics

Y Li, J Xuan, Y Song, P Wang, L Qin - Lab on a Chip, 2015‏ - pubs.rsc.org
Quantitative assays are of great importance for point-of-care (POC) diagnostics because
they can offer accurate information on the analytes. However, current POC devices often …

A Printed Paper‐Based Anion Sensor Array for Multi‐Analyte Classification: On‐Site Quantification of Glyphosate

Z Zhang, V Hamedpour, X Lyu, Y Sasaki… - …, 2021‏ - Wiley Online Library
We report a paper‐based chemosensor array device (PCSAD) for the quantitative detection
of oxyanions including the herbicide glyphosate (GlyP) in aqueous media. The mechanism …

Bubble breakup with permanent obstruction in an asymmetric microfluidic T‐junction

X Wang, C Zhu, T Fu, Y Ma - AIChE Journal, 2015‏ - Wiley Online Library
Bubble breakup with permanent obstruction in an asymmetric microfluidic T‐junction is
investigated experimentally. The breakup process of bubbles can be divided into three …

Detection of renal biomarkers in chronic kidney disease using microfluidics: Progress, challenges and opportunities

KZ Liu, G Tian, ACT Ko, M Geissler, D Brassard… - Biomedical …, 2020‏ - Springer
Chronic kidney disease (CKD) typically evolves over many years in a latent period without
clinical signs, posing key challenges to detection at relatively early stages of the disease …