Myopia is the most common eye condition leading to visual impairment and is greatly
influenced by genetics. Over the last two decades, more than 400 associated gene loci have …

Myopia is a globally emerging concern accompanied by multiple medical and socio-
economic burdens with no well-established causal treatment to control thus far. The study of …

Vertebrates rely on rod photoreceptors for vision in low-light conditions. The specialized
downstream circuit for rod signalling, called the primary rod pathway, is well characterized in …

Myopia most often develops during school age, with the highest incidence in countries with
intensive education systems. Interactions between genetic variants and educational …

Purpose To elucidate the differences in ocular biometric parameters by generation and
gender and to identify axial length (AL)-associated genetic variants in Japanese individuals …

Bioelectric signaling, intercellular communication facilitated by membrane potential and
electrochemical coupling, is emerging as a key regulator of animal development. Gap …

The etiology of myopia remains unclear. This study investigated whether retinal ganglion
cells (RGCs) in the myopic retina encode visual information differently from the normal retina …

Myopia is a refractive disorder arising from a mismatch between refractive power and
relatively long axial length of the eye. With its dramatically increasing prevalence, myopia …

Cell-to-cell communication through gap junction channels is very important to coordinate the
functions of cells in all multicellular biological tissues. It allows the direct exchange of ions …

Genome-wide association studies (GWAS) have dissected numerous genetic factors
underlying refractive errors (RE) such as myopia. Despite significant insights into …