Matrix metalloproteinases in chemoresistance: regulatory roles, molecular interactions, and potential inhibitors
Cancer is one of the major causes of death worldwide. Its treatments usually fail when the
tumor has become malignant and metastasized. Metastasis is a key source of cancer …
tumor has become malignant and metastasized. Metastasis is a key source of cancer …
Liquid biopsy to detect minimal residual disease: methodology and impact
Simple Summary The field of liquid biopsy is rapidly evolving. Techniques that improve
accuracy are constantly being developed, and clinicians increasingly use liquid biopsy as a …
accuracy are constantly being developed, and clinicians increasingly use liquid biopsy as a …
Evodiamine as an anticancer agent: a comprehensive review on its therapeutic application, pharmacokinetic, toxicity, and metabolism in various cancers
Evodiamine is a major alkaloid component found in the fruit of Evodia rutaecarpa. It shows
the anti-proliferative potential against a wide range of cancers by suppressing cell growth …
the anti-proliferative potential against a wide range of cancers by suppressing cell growth …
Antiviral peptides against SARS-CoV-2: therapeutic targets, mechanistic antiviral activity, and efficient delivery
The global pandemic of COVID-19 is a serious public health concern. Over 625 million
confirmed cases and more than 6 million deaths have been recorded worldwide. Although …
confirmed cases and more than 6 million deaths have been recorded worldwide. Although …
Exosomal long non-coding RNAs: novel molecules in gastrointestinal cancers' progression and diagnosis
Gastrointestinal (GI) cancers arise in the GI tract and accessory organs, including the mouth,
esophagus, stomach, liver, biliary tract, pancreas, small intestine, large intestine, and …
esophagus, stomach, liver, biliary tract, pancreas, small intestine, large intestine, and …
[HTML][HTML] LncRNA UCA1 mediates Cetuximab resistance in Colorectal Cancer via the MiR-495 and HGF/c-MET Pathways
H Yuan, X Zhang, X Wei, W Zhang, X Du… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background: Cetuximab is one of the most widely used monoclonal antibodies to treat
patients with RAS/BRAF wild-type metastatic colorectal cancer (mCRC). Unfortunately …
patients with RAS/BRAF wild-type metastatic colorectal cancer (mCRC). Unfortunately …
Long noncoding RNAs in ubiquitination, protein degradation, and human diseases
Protein stability and turnover is critical in normal cellular and physiological process and their
misregulation may contribute to accumulation of unwanted proteins causing cellular …
misregulation may contribute to accumulation of unwanted proteins causing cellular …
UCA1 executes an oncogenic role in pancreatic cancer by regulating miR-582-5p/BRCC3
X Hu, J Wu, J Xu - Frontiers in Oncology, 2023 - frontiersin.org
Background As a fatal disease, the mechanism of pancreatic cancer is unclear. Urothelial
carcinoma antigen 1 (UCA1), a long noncoding RNA (lncRNA) that was first reported in …
carcinoma antigen 1 (UCA1), a long noncoding RNA (lncRNA) that was first reported in …
Phytochemicals of Withania somnifera as a Future Promising Drug against SARS-CoV-2: Pharmacological Role, Molecular Mechanism, Molecular Docking …
Coronavirus disease (COVID-19) has killed millions of people since first reported in Wuhan,
China, in December 2019. Intriguingly, Withania somnifera (WS) has shown promising …
China, in December 2019. Intriguingly, Withania somnifera (WS) has shown promising …
Long noncoding competing endogenous RNA networks in pancreatic cancer
G **ong, S Pan, J **, X Wang, R He, F Peng… - Frontiers in …, 2021 - frontiersin.org
Pancreatic cancer (PC) is a highly malignant disease characterized by insidious onset, rapid
progress, and poor therapeutic effects. The molecular mechanisms associated with PC …
progress, and poor therapeutic effects. The molecular mechanisms associated with PC …