Bacterial ghosts as adjuvants: mechanisms and potential

IA Hajam, PA Dar, G Won, JH Lee - Veterinary Research, 2017 - Springer
Bacterial ghosts (BG) are empty cell envelopes derived from Gram-negative bacteria. They
contain many innate immunostimulatory agonists, and are potent activators of a broad range …

Phage lytic proteins: biotechnological applications beyond clinical antimicrobials

L Rodríguez-Rubio, D Gutiérrez… - Critical reviews in …, 2016 - Taylor & Francis
Most bacteriophages encode two types of cell wall lytic proteins: endolysins (lysins) and
virion-associated peptidoglycan hydrolases. Both enzymes have the ability to degrade the …

[BUCH][B] Encyclopedia of microbiology

TM Schmidt - 2019 - books.google.com
Encyclopedia of Microbiology, Fourth Edition, Five Volume Set gathers both basic and
applied dimensions in this dynamic field that includes virtually all environments on Earth …

Bacterial Ghosts as an Oral Vaccine: a Single Dose of Escherichia coli O157:H7 Bacterial Ghosts Protects Mice against Lethal Challenge

UB Mayr, C Haller, W Haidinger… - Infection and …, 2005 - Am Soc Microbiol
Enterohemorrhagic Escherichia coli (EHEC) is a bacterial pathogen that is associated with
several life-threatening diseases for humans. The combination of protein E-mediated cell …

Bacterial ghosts are an efficient delivery system for DNA vaccines

T Ebensen, S Paukner, C Link, P Kudela… - The Journal of …, 2004 - journals.aai.org
Mass implementation of DNA vaccines is hindered by the requirement of high plasmid
dosages and poor immunogenicity. We evaluated the capacity of Mannheimia haemolytica …

Bacterial ghosts as antigen delivery vehicles

UB Mayr, P Walcher, C Azimpour, E Riedmann… - Advanced drug delivery …, 2005 - Elsevier
The bacterial ghost system is a novel vaccine delivery system unusual in that it combines
excellent natural intrinsic adjuvant properties with versatile carrier functions for foreign …

Mucosal vaccine delivery of antigens tightly bound to an adjuvant particle made from food-grade bacteria

ML van Roosmalen, R Kanninga, M El Khattabi, J Neef… - Methods, 2006 - Elsevier
Mucosal immunization with subunit vaccines requires new types of antigen delivery vehicles
and adjuvants for optimal immune responses. We have developed a non-living and non …

Development of immunization trials against Pasteurella multocida

TA Ahmad, SS Rammah, SA Sheweita, M Haroun… - Vaccine, 2014 - Elsevier
Pasteurellosis is one of the most important respiratory diseases facing economically
valuable farm animals such as poultry, rabbit, cattle, goats and pigs. It causes severe …

The development of ghost vaccines trials

AM Batah, TA Ahmad - Expert review of vaccines, 2020 - Taylor & Francis
Introduction Bacterial ghosts are intact bacterial cell envelopes that are emptied of their
content by gentle biological or chemical poring methods. Ghost techniques increase the …

Protection of tilapia (Oreochromis mosambicus) from edwardsiellosis by vaccination with Edwardsiella tarda ghosts

SR Kwon, YK Nam, SK Kim, KH Kim - Fish & shellfish immunology, 2006 - Elsevier
The vaccine potential of Edwardsiella tarda ghosts produced by gene E mediated lysis was
investigated using tilapia (Oreochromis mosambicus). Tilapia immunized with E. tarda …