[HTML][HTML] Structural genomics of SARS-CoV-2 indicates evolutionary conserved functional regions of viral proteins

S Srinivasan, H Cui, Z Gao, M Liu, S Lu, W Mkandawire… - Viruses, 2020 - mdpi.com
During its first two and a half months, the recently emerged 2019 novel coronavirus, SARS-
CoV-2, has already infected over one-hundred thousand people worldwide and has taken …

A multi-pronged approach targeting SARS-CoV-2 proteins using ultra-large virtual screening

C Gorgulla, KMP Das, KE Leigh, M Cespugli… - Iscience, 2021 - cell.com
The unparalleled global effort to combat the continuing severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) pandemic over the last year has resulted in promising …

A nascent peptide code for translational control of mRNA stability in human cells

PC Burke, H Park, AR Subramaniam - Nature Communications, 2022 - nature.com
Stability of eukaryotic mRNAs is associated with their codon, amino acid, and GC content.
Yet, coding sequence motifs that predictably alter mRNA stability in human cells remain …

Structural genomics and interactomics of 2019 Wuhan novel coronavirus, 2019-nCoV, indicate evolutionary conserved functional regions of viral proteins

H Cui, Z Gao, M Liu, S Lu, S Mo, W Mkandawire… - biorxiv, 2020 - biorxiv.org
During its first month, the recently emerged 2019 Wuhan novel coronavirus (2019-nCoV)
has already infected many thousands of people in mainland China and worldwide and took …

Codon usage bias of secretory protein in Fusarium oxysporum f. sp. cubense tropical race 4

H Fang, M Li, S Yu, J Sun, Z Qin - Journal of Basic Microbiology, 2024 - Wiley Online Library
Banana Fusarium oxysporum f. sp. cubense tropical race 4 (Foc‐TR4) is a highly destructive
pathogen that infects nearly all major banana cultivars and has a tendency to spread further …

Broad diversity of simian immunodeficiency virus infecting Chlorocebus species (African green monkey) and evidence of cross‐species infection in Papio anubis …

R Nyamota, V Owino, EK Murungi… - Journal of Medical …, 2020 - Wiley Online Library
Background Simian immunodeficiency virus (SIV) naturally infects African non‐human
primates (NHPs) and poses a threat of transmission to humans through hunting and …

Structural Genomics and Interactomics of SARS-COV2: Decoding Basic Building Blocks of the Coronavirus

Z Gao, S Lu, O Narykov, S Srinivasan… - Virus …, 2021 - taylorfrancis.com
By November 2020, over 60 million people in 218 countries have been infected with COVID-
19, with the number of deaths rapidly approaching 1.5 million and the second wave of …

Computational Analysis of Druggability and Genetic Variability of SARS-CoV-2 Pocketome

S Yazdani - 2021 - search.proquest.com
Emerging novel coronaviruses (CoVs) and new variants of SARS-CoV-2 are a major public
health threat. One therapeutic strategy to face this challenge is to develop broad-spectrum …

Developmental Abnormalities In Human Induced Neurons And Neural Precursor Cells Derived From Patients With Idiopathic Autism And Chromosome 16p11. 2 …

M Mehta - 2021 - rucore.libraries.rutgers.edu
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder
characterized by developmental delay, social deficits, and restricted, repetitive behaviors …

In-SilicoStructure-Based Drug Discovery of Candidate Drugs against Novel Protein Receptor Complex Nsp10-Nsp16 of SARS-CoV-2 using Drug Repurposing …

A Sengupta, P Vijayaraghavan, P Srivastava… - …, 2021 - benthamdirect.com
Background: Several therapeutic possibilities have been explored against Severe Acute
Respiratory Syndrome-2 (SARS-CoV-2), such as convalescent plasma (CP), intravenous …