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Exosomes as a new frontier of cancer liquid biopsy
D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …
Circulating tumour DNA—looking beyond the blood
Over the past decade, various liquid biopsy techniques have emerged as viable alternatives
to the analysis of traditional tissue biopsy samples. Such surrogate 'biopsies' offer numerous …
to the analysis of traditional tissue biopsy samples. Such surrogate 'biopsies' offer numerous …
Tumor-derived extracellular vesicles: multifunctional entities in the tumor microenvironment
JW Clancy, C D'Souza-Schorey - Annual Review of Pathology …, 2023 - annualreviews.org
Tumor cells release extracellular vesicles (EVs) that can function as mediators of
intercellular communication in the tumor microenvironment. EVs contain a host of bioactive …
intercellular communication in the tumor microenvironment. EVs contain a host of bioactive …
[HTML][HTML] The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring
The emerging field of liquid biopsy stands at the forefront of novel diagnostic strategies for
cancer and other diseases. Liquid biopsy allows minimally invasive molecular …
cancer and other diseases. Liquid biopsy allows minimally invasive molecular …
Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …
cargo comprising several populations with unique roles in biological processes. These …
Extracellular vesicles: A bright star of nanomedicine
P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …
characteristics as well as predominant physiochemical stability and biocompatibility …
Clinical implications of intratumor heterogeneity: challenges and opportunities
S Ramón y Cajal, M Sesé, C Capdevila… - Journal of Molecular …, 2020 - Springer
In this review, we highlight the role of intratumoral heterogeneity, focusing on the clinical and
biological ramifications this phenomenon poses. Intratumoral heterogeneity arises through …
biological ramifications this phenomenon poses. Intratumoral heterogeneity arises through …
New technologies for analysis of extracellular vesicles
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
Future of digital assays to resolve clinical heterogeneity of single extracellular vesicles
Extracellular vesicles (EVs) are complex lipid membrane vehicles with variable expressions
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …
of molecular cargo, composed of diverse subpopulations that participate in the intercellular …
Technical challenges of working with extracellular vesicles
Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …
potential applications in diagnosis, prognosis and therapeutic guidance in most pathological …