Digital twins in pharmaceutical and biopharmaceutical manufacturing: a literature review
The development and application of emerging technologies of Industry 4.0 enable the
realization of digital twins (DT), which facilitates the transformation of the manufacturing …
realization of digital twins (DT), which facilitates the transformation of the manufacturing …
Bioprocessing in the digital age: the role of process models
In this age of technology, the vision of manufacturing industries built of smart factories is not
a farfetched future. As a prerequisite for Industry 4.0, industrial sectors are moving towards …
a farfetched future. As a prerequisite for Industry 4.0, industrial sectors are moving towards …
Machine learning for biologics: opportunities for protein engineering, developability, and formulation
Successful biologics must satisfy multiple properties including activity and particular
physicochemical features that are globally defined as developability. These multiple …
physicochemical features that are globally defined as developability. These multiple …
Bioprocess control: current progress and future perspectives
Typical bioprocess comprises of different unit operations wherein a near optimal
environment is required for cells to grow, divide, and synthesize the desired product …
environment is required for cells to grow, divide, and synthesize the desired product …
Advancements in SPR biosensing technology: An overview of recent trends in smart layers design, multiplexing concepts, continuous monitoring and in vivo sensing
Inspired by the rapid progress and existing limitations in surface plasmon resonance (SPR)
biosensing technology, we have summarized the recent trends in the fields of both chip-SPR …
biosensing technology, we have summarized the recent trends in the fields of both chip-SPR …
Biopharmaceutical manufacturing: Historical perspectives and future directions
AC Szkodny, KH Lee - Annual Review of Chemical and …, 2022 - annualreviews.org
This review describes key milestones related to the production of biopharmaceuticals—
therapies manufactured using recombinant DNA technology. The market for …
therapies manufactured using recombinant DNA technology. The market for …
Process analytical technologies and data analytics for the manufacture of monoclonal antibodies
Process analytical technology (PAT) for the manufacture of monoclonal antibodies (mAbs) is
defined by an integrated set of advanced and automated methods that analyze the …
defined by an integrated set of advanced and automated methods that analyze the …
Bioprocess systems analysis, modeling, estimation, and control
The production of monoclonal antibody (mAb) therapeutics, a rapidly growing multi-billion-
dollar enterprise in the biopharmaceutical industry, faces major challenges in achieving …
dollar enterprise in the biopharmaceutical industry, faces major challenges in achieving …
Recent trends in AI-based intelligent sensing
In recent years, intelligent sensing has gained significant attention because of its
autonomous decision-making ability to solve complex problems. Today, smart sensors …
autonomous decision-making ability to solve complex problems. Today, smart sensors …
Recent advances in integrated process analytical techniques, modeling, and control strategies to enable continuous biomanufacturing of monoclonal antibodies
Continuous bioprocessing is significantly changing the biological drugs (or biologics)
manufacturing landscape by potentially improving product quality, process stability, and …
manufacturing landscape by potentially improving product quality, process stability, and …