New insights into natural products that target the gut microbiota: Effects on the prevention and treatment of colorectal cancer

L Lu, J Dong, Y Liu, Y Qian, G Zhang, W Zhou… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignant carcinomas. CRC is
characterized by asymptomatic onset, and most patients are already in the middle and …

Dietary flavonoids and gut microbiota interaction: A focus on animal and human studies to maximize their health benefits

L Yang, Y Gao, MA Farag, J Gong, Q Su, H Cao… - Food …, 2023 - Wiley Online Library
Flavonoids are phytochemicals that widely exist in plants, fruits, and vegetables and have a
variety of activities. However, due to their complex structure, it is often rarely absorbed into …

Oroxylin A: A promising flavonoid for prevention and treatment of chronic diseases

A Sajeev, M Hegde, S Girisa, TN Devanarayanan… - Biomolecules, 2022 - mdpi.com
There have been magnificent advancements in the understanding of molecular mechanisms
of chronic diseases over the past several years, but these diseases continue to be a …

Treatment effects of natural products on inflammatory bowel disease in vivo and their mechanisms: Based on animal experiments

Y Zhou, D Wang, W Yan - Nutrients, 2023 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic, non-specific inflammatory disease of the
intestine that can be classified as ulcerative colitis (UC) and Crohn's disease (CD) …

Dietary flavonoids–microbiota crosstalk in intestinal inflammation and carcinogenesis

L Wang, M Li, Y Gu, J Shi, J Yan, X Wang, B Li… - The Journal of …, 2024 - Elsevier
Colorectal cancer (CRC) is currently the third leading cancer and commonly develops from
chronic intestinal inflammation. A strong association was found between gut microbiota and …

Discovery of anti-inflammatory natural flavonoids: Diverse scaffolds and promising leads for drug discovery

J Li, R Zhao, P Miao, F Xu, J Chen, X Jiang… - European Journal of …, 2023 - Elsevier
Natural products have been utilized for medicinal purposes for millennia, endowing them
with a rich source of chemical scaffolds and pharmacological leads for drug discovery …

Undaria pinnatifida fucoidan contributes to anti-inflammation activity of Bacteroides in fiber-deficient mice via modulation of gut microbiota and protection of intestinal …

W Zheng, J Jia, S Tang, S Song, C Ai - International Journal of Biological …, 2023 - Elsevier
Bacteroides as potential probiotics has several health benefits to the host, but its practical
application faces many challenges due to its inherent properties. In this study, Bacteroides …

[HTML][HTML] Environmental hexavalent chromium exposure induces gut microbial dysbiosis in chickens

A Li, J Ding, T Shen, Z Han, J Zhang… - Ecotoxicology and …, 2021 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a hazardous heavy metal that pollutes soil, water
and crops. Moreover, its prolonged exposure can harm the gastrointestinal system, liver and …

Moutai Distiller's grains Polyphenol extracts and rutin alleviate DSS-induced colitis in mice: Modulation of gut microbiota and intestinal barrier function (R2)

J Chen, C Zhao, Y Li, Y Yang, J Luo, C Zhang, L Wang - Heliyon, 2023 - cell.com
Distiller's grains, byproducts of the brewing process, represent a valuable resource for
extracting natural phenolic compounds due to their significant global production. This study …

The many ages of microbiome–gut–brain axis

D Ratto, E Roda, M Romeo, MT Venuti, A Desiderio… - Nutrients, 2022 - mdpi.com
Frailty during aging is an increasing problem associated with locomotor and cognitive
decline, implicated in poor quality of life and adverse health consequences. Considering the …