HaloTag technology: a versatile platform for biomedical applications
Exploration of protein function and interaction is critical for discovering links among
genomics, proteomics, and disease state; yet, the immense complexity of proteomics found …
genomics, proteomics, and disease state; yet, the immense complexity of proteomics found …
Studying protein–protein interactions using peptide arrays
C Katz, L Levy-Beladev, S Rotem-Bamberger… - Chemical Society …, 2011 - pubs.rsc.org
Screening of arrays and libraries of compounds is well-established as a high-throughput
method for detecting and analyzing interactions in both biological and chemical systems …
method for detecting and analyzing interactions in both biological and chemical systems …
Haloalkane dehalogenases: biotechnological applications
T Koudelakova, S Bidmanova, P Dvorak… - Biotechnology …, 2013 - Wiley Online Library
Abstract Haloalkane dehalogenases (EC 3.8. 1.5, HLDs) are α/β‐hydrolases which act to
cleave carbon‐halogen bonds. Due to their unique catalytic mechanism, broad substrate …
cleave carbon‐halogen bonds. Due to their unique catalytic mechanism, broad substrate …
Identification and characterization of small molecule inhibitors of a plant homeodomain finger
A number of histone-binding domains are implicated in cancer through improper binding of
chromatin. In a clinically reported case of acute myeloid leukemia (AML), a genetic fusion …
chromatin. In a clinically reported case of acute myeloid leukemia (AML), a genetic fusion …
Recent advances in microarray technologies for proteomics
Proteins are fundamental components of all living systems and critical drivers of biological
functions. The large-scale study of proteins, their structures and functions, is defined as …
functions. The large-scale study of proteins, their structures and functions, is defined as …
Evolution of sequence-based bioinformatics tools for protein-protein interaction prediction
Protein-protein interactions (PPIs) are the physical connections between two or more
proteins via electrostatic forces or hydrophobic effects. Identification of the PPIs is pivotal …
proteins via electrostatic forces or hydrophobic effects. Identification of the PPIs is pivotal …
Chemoselective and bioorthogonal ligation reactions: concepts and applications
This timely, one-stop reference is the first on an emerging and interdisciplinary topic.
Covering both established and recently developed ligation chemistries, the book is divided …
Covering both established and recently developed ligation chemistries, the book is divided …